IL-8 Protein (AA 23-99)
Quick Overview for IL-8 Protein (AA 23-99) (ABIN1096965)
抗原
See all IL-8 (IL8) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
-
-
产品特性
- AA 23-99
-
原理
- Recombinant Human Interleukin-8/IL-8 (Ala23-Ser99)
-
序列
- AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
-
产品特性
- Recombinant Human Interleukin-8/IL-8 (3-79) produced in E. coli is a single non-glycosylated polypeptide chain containing 77 amino acids with a molecular mass of 8,904 Daltons.
-
过滤
- 0.2 μm filtered
-
内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
-
-
-
-
说明
-
Biological activity: Recombinant IL-8 (3-79) is fully biologically active when compared to standards.ED50 is less than 2 ng/ml as determined by its chemotaxis of hCXCR-2 transfected mouse BaF/3 cells.Specific Activity of 5.0 x 105 IU/mg.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
-
注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
-
储存条件
- 4 °C/-20 °C/-80 °C
-
储存方法
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
-
-
- IL-8 (IL8) (Interleukin 8 (IL8))
-
别名
- Il-8-77
-
背景
-
Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.
Alternative Names: Interleukin-8, IL-8, C-X-C Motif Chemokine 8, Emoctakin, Granulocyte Chemotactic Protein 1, GCP-1, Monocyte-Derived Neutrophil Chemotactic Factor, MDNCF, Monocyte-Derived Neutrophil-Activating Peptide, MONAP, Neutrophil-Activating Protein 1, NAP-1, Protei -
分子量
- 8.9 kDa
-
UniProt
- P10145
-
途径
- TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
抗原
-