CD44 Protein (CD44) (AA 21-220) (His tag)
Quick Overview for CD44 Protein (CD44) (AA 21-220) (His tag) (ABIN1691275)
抗原
See all CD44 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 21-220
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标记
- This CD44 protein is labelled with His tag.
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原理
- Recombinant Human CD44/MIC4 (C-6His)
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序列
- QIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDSP WITDSTDRIP VDHHHHHH
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产品特性
- Recombinant Human CD44 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln21-Pro220) of Human CD44 fused with a polyhistidine tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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CD44 (CD44) (AA 1-699) protein (GST tag)
CD44 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD44 (CD44) (AA 152-311) protein (His-IF2DI Tag)CD44 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
CD44 (CD44) (AA 1-361) protein (GST tag)CD44 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD44 (CD44) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CD44 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
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- CD44
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别名
- cd44
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Sub Type
- Fusionprotein
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背景
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CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one.
Alternative Names: CD44 Antigen, CDw44, Epican, Extracellular Matrix Receptor III, ECMR-III, GP90 Lymphocyte Homing/Adhesion Receptor, HUTCH-I, Heparan Sulfate Proteoglycan, Hermes Antigen, Hyaluronate Receptor, Phagocytic Glycoprotein 1, PGP-1, Phagocytic Glycoprotein I, P -
分子量
- 23.1 kDa
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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