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抗Rat (Rattus) NUP153 抗体:
抗Mouse (Murine) NUP153 抗体:
抗Human NUP153 抗体:
Rat (Rattus) Monoclonal NUP153 Primary Antibody for ICC, IF - ABIN2452062
Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: Nanomechanical basis of selective gating by the nuclear pore complex. in Science (New York, N.Y.) 2007
Show all 2 Pubmed References
Human Polyclonal NUP153 Primary Antibody for ICC, IF - ABIN408608
Wan, Zhang, Langley, Liu, Hu, Han, Peng, Ellis, Jones, Lu: DNA-damage-induced nuclear export of precursor microRNAs is regulated by the ATM-AKT pathway. in Cell reports 2013
Human Polyclonal NUP153 Primary Antibody for IP, WB - ABIN408609
Watters, Palmenberg: Differential processing of nuclear pore complex proteins by rhinovirus 2A proteases from different species and serotypes. in Journal of virology 2011
Nup153 and Megator (Mtor (显示 FRAP1 抗体)) bind to 25% of the genome in continuous domains extending 10 kb to 500 kb.
The FG repeats of Nup153 are necessary for its function in transport, whereas the remainder of the protein maintains pore integrity.
Nup153 and Sox2 (显示 SOX2 抗体) bind and co-regulate hundreds of genes.
Nup50 (显示 NUP50 抗体) dynamics are independent of importin alpha, Nup153, and Nup98 (显示 NUP98 抗体), even though the latter two proteins also exhibit transcription-dependent mobility.
results demonstrate a chromatin-associated role of Nup153 in maintaining stem cell pluripotency by functioning in mammalian epigenetic gene silencing
Nup153 is essential for the HIV-1 nuclear import in nondividing cells, and CPSF6 (显示 CPSF6 抗体) is important for HIV-1 integration.
Despite the requirement of all three nucleoporins for accurate NHEJ, only Nup153 is needed for proper nuclear import of 53BP1 (显示 TP53BP1 抗体) and SENP1 (显示 SENP1 抗体)-dependent sumoylation of 53BP1 (显示 TP53BP1 抗体). Our data support the role of Nup153 as an important regulator of 53BP1 (显示 TP53BP1 抗体) activity and efficient NHEJ.
results further highlight the antagonistic relationship between 53BP1 and BRCA1, and place Nup153 and Nup50 in a molecular pathway that regulates 53BP1 function by counteracting BRCA1-mediated events.
Nup153 is an epigenetic regulator which, upon altered NO signalling, mediates the activation of genes potentially associated with early dystrophic cardiac remodelling.
NUP153 and CPSF6 (显示 CPSF6 抗体) have overlapping binding sites, but each makes unique capsid monomers (CA) interactions. Multiple ligands share an overlapping interface in HIV-1 capsid that is lost upon viral disassembly.
Study assessed the extent of collapse of a Nup153 fragment in molecular dynamics simulations and compared the results to single molecule FRET and small-angle X-ray scattering experiments of this peptide
Our data indicate a central function of Nup153 in the organization of the nucleus, not only at the periphery, but throughout the entire nuclear interior.
Nucleoporin Nup153 is required for NPC (显示 NPC1 抗体) assembly during interphase but not during mitotic exit. It functions in interphasic NPC (显示 NPC1 抗体) formation by binding directly to the inner nuclear membrane via an N-terminal amphipathic helix.
The data presented here suggest that BGLF4 interferes with the normal functions of Nup62 (显示 NUP62 抗体) and Nup153 and preferentially helps the nuclear import of viral proteins for viral DNA replication and assembly.
These data reveal an emergent Kap (显示 CDKN3 抗体)-centric barrier mechanism that may underlie mechanistic and kinetic control in the nuclear pore complex.
analysis of RNA recognition sequence preference by the nucleoporin Nup153
Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex-specific glycoproteins characterized by cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. The protein encoded by this gene has three distinct domains: a N-terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.
, nucleoporin 153
, nuclear pore complex protein Nup153
, nucleoporin 153kDa
, nuclear pore complex protein Nup153-like
, 153 kDa nucleoporin
, nucleoporin 153kD
, nucleoporin Nup153
, nuclear pore complex protein hnup153