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NUP153 抗体 (AA 610-1191)

NUP153 适用: 大鼠 WB, ELISA, IF, ICC 宿主: 大鼠 Monoclonal R4C8 unconjugated
产品编号 ABIN2452062
发货至: 中国
  • 抗原 See all NUP153 抗体
    NUP153 (Nucleoporin 153kDa (NUP153))
    抗原表位
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 610-1191
    适用
    • 41
    • 13
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 40
    • 1
    • 1
    大鼠
    克隆类型
    • 31
    • 11
    单克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This NUP153 antibody is un-conjugated
    应用范围
    • 22
    • 11
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Specific to human, mouse, rat and monkey Nup153 proteins.
    交叉反应 (详细)
    Not tested for other species
    产品特性
    When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.
    纯化方法
    Purified
    过滤
    Sterile filtered
    免疫原
    Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)
    克隆位点
    R4C8
    亚型
    IgG2a kappa
  • 应用备注
    1. Western blotting: 160 kDa single band in Hela cell extract
    2. Immunocytochemistry
    3. ELISA
    Other applications have not been tested.

    Additional comments:
    When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
    R4C8 works in immuno-cytochemistry very well.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol
    储存液
    Azide free
    储存条件
    -20 °C
    储存方法
    Upon receipt aliquot and store at -20 C
  • Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: "Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).

    Ullman, Shah, Powers, Forbes: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." in: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, (1999) (PubMed).

  • 抗原
    NUP153 (Nucleoporin 153kDa (NUP153))
    别名
    Nup153 (NUP153 产品)
    别名
    CG4453 antibody, Dmel\\CG4453 antibody, NUP153 antibody, Nup 153 antibody, dNup153 antibody, dmNup153 antibody, nup153 antibody, NUCZINK antibody, B130015D15Rik antibody, C88147 antibody, HNUP153 antibody, N153 antibody, Nucleoporin 153kD antibody, nucleoporin 153 antibody, nucleoporin 153kDa L homeolog antibody, Nup153 antibody, NUP153 antibody, nup153.L antibody
    背景
    The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.
    UniProt
    P49790
    途径
    Protein targeting to Nucleus
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