Protein Kinase C, theta 抗体
(Protein Kinase C, theta (PRKCQ))
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008].
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PRKCQ
适用: 人, 大鼠, 小鼠, Cow, 犬, Pig, 猴
WB, IHC, IF, IHC (p), ICC
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our Protein Kinase C, theta 抗体
: "Evidence of microglial activation following exposure to serum from first-onset drug-naïve schizophrenia patients." in: Brain, behavior, and immunity, Vol. 67, pp. 364-373, (2018) (PubMed).
: "Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells." in: The FEBS journal, Vol. 273, Issue 8, pp. 1843-54, (2006) (PubMed).
: "Catalytic domain crystal structure of protein kinase C-theta (PKCtheta)." in: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 50401-9, (2004) (PubMed).
: "Characterization of TCR-induced phosphorylation of PKCtheta in primary murine lymphocytes." in: Molecular immunology, Vol. 40, Issue 13, pp. 931-42, (2004) (PubMed).
: "Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in ..." in: Blood, Vol. 103, Issue 3, pp. 948-54, (2004) (PubMed).
: "Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta." in: The Journal of biological chemistry, Vol. 279, Issue 18, pp. 18623-32, (2004) (PubMed).
: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).
: "Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes." in: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2932-42, (2004) (PubMed).
: "Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28315-9, (2004) (PubMed).
: "A Ras activation pathway dependent on Syk phosphorylation of protein kinase C." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 16, pp. 9470-5, (2003) (PubMed).
: "Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells." in: The FEBS journal, Vol. 273, Issue 8, pp. 1843-54, (2006) (PubMed).
: "Catalytic domain crystal structure of protein kinase C-theta (PKCtheta)." in: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 50401-9, (2004) (PubMed).
: "Characterization of TCR-induced phosphorylation of PKCtheta in primary murine lymphocytes." in: Molecular immunology, Vol. 40, Issue 13, pp. 931-42, (2004) (PubMed).
: "Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in ..." in: Blood, Vol. 103, Issue 3, pp. 948-54, (2004) (PubMed).
: "Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta." in: The Journal of biological chemistry, Vol. 279, Issue 18, pp. 18623-32, (2004) (PubMed).
: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).
: "Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes." in: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2932-42, (2004) (PubMed).
: "Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28315-9, (2004) (PubMed).
: "A Ras activation pathway dependent on Syk phosphorylation of protein kinase C." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 16, pp. 9470-5, (2003) (PubMed).
Aliases for Protein Kinase C, theta 抗体
protein kinase C theta (PRKCQ) 抗体protein kinase C, theta (Prkcq) 抗体
protein kinase C eta (PRKCH) 抗体
proline rich transmembrane protein 2 (PRRT2) 抗体
protein kinase C theta (Prkcq) 抗体
protein kinase C, theta (prkcq) 抗体
A130035A12Rik 抗体
AW494342 抗体
BFIC2 抗体
BFIS2 抗体
DSPB3 抗体
DYT10 抗体
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nPKC-theta 抗体
PKC 抗体
PKC-0 抗体
PKC-theta 抗体
Pkcq 抗体
PKCtheta 抗体
PRKCT 抗体
si:ch211-239o15.1 抗体
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