PKC theta 抗体 (pSer695)
Our Local Distributor
北京 101111
Quick Overview for PKC theta 抗体 (pSer695) (ABIN1531509)
抗原
See all PKC theta (PRKCQ) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 657-706, pSer695
-
原理
- PKC θ (phospho Ser695) Antibody
-
特异性
- Phospho-PKC θ (S695) Polyclonal Antibody detects endogenous levels of PKC θ protein only when phosphorylated at S695.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human PKC thet around the phosphorylation site of Ser695. AA range:657-706
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
-
别名
- PKC theta
-
背景
-
Synonyms: PRKCQ, PRKCT, Protein kinase C theta type, nPKC-theta
Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role.The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008],
Gene Name: PRKCQ
Protein Name: Protein kinase C theta type
-
分子量
- 81 kDa
-
基因ID
- 5588
-
OMIM
- 600448
-
UniProt
- Q04759
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
-