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PKC theta 抗体 (pSer695)

PRKCQ 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138681
发货至: 中国
  • 抗原 See all PKC theta (PRKCQ) 抗体
    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
    抗原表位
    • 31
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    pSer695
    适用
    • 89
    • 66
    • 54
    • 6
    • 5
    • 5
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    • 3
    • 2
    • 1
    • 1
    宿主
    • 116
    • 2
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    克隆类型
    • 118
    • 3
    多克隆
    标记
    • 60
    • 6
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    This PKC theta antibody is un-conjugated
    应用范围
    • 102
    • 41
    • 40
    • 40
    • 33
    • 24
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of serine 695 (N-F-S(p)-F-M) derived from Human PKCth.
    亚型
    IgG
    Top Product
    Discover our top product PRKCQ Primary Antibody
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
    别名
    PRKCQ (PRKCQ 产品)
    别名
    PRKCT antibody, nPKC-theta antibody, A130035A12Rik antibody, AW494342 antibody, PKC-0 antibody, PKC-theta antibody, PKCtheta antibody, Pkcq antibody, protein kinase C theta antibody, protein kinase C eta antibody, protein kinase C, theta antibody, PRKCQ antibody, PRKCH antibody, Prkcq antibody
    背景

    Background: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

    Xu ZB, et al.(2004) J Biol Chem 279:50401-50409
    Thebault S, et al. (2004) Mol Immunol 40: 931-942

    Aliases: KPCT_HUMAN antibody, MGC126514 antibody, MGC141919 antibody, nPKC theta antibody, nPKC-theta antibody, nPKCtheta antibody, OTTHUMP00000043364 antibody, OTTHUMP00000043365 antibody, PKC 0 antibody, PKC0 antibody, Prkcq antibody, PRKCT antibody, Protein kinase C theta antibody, Protein kinase C theta type antibody, Protein Kinase Ctheta antibody

    UniProt
    Q04759
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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