PREX2 蛋白
(DEP Domain Containing 2 (DEPDC2))
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase (By similarity).
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4 results
DEPDC2
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aliases for PREX2 蛋白
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 (PREX2) 蛋白phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2) 蛋白
6230420N16Rik 蛋白
AI316880 蛋白
AI553603 蛋白
C030045D06Rik 蛋白
D430013K02 蛋白
DEP.2 蛋白
DEPDC2 蛋白
Depdc2 蛋白
P-REX2 蛋白
P-Rex2 蛋白
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