Premelanosome Protein 蛋白
(Premelanosome Protein (PMEL))
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Melanoma gp100 Protein (AA 1-661) (GST tag) | 人 | 小麦胚 |
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| Melanoma gp100 Protein (AA 25-545) (Fc Tag) | 人 | HEK-293 Cells |
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| Melanoma gp100 Protein (AA 470-661) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Melanoma gp100 Protein (AA 25-467) (His tag) | 人 | 酵母菌 |
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| Melanoma gp100 Protein (AA 25-467) (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| Melanoma gp100 Protein (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| Melanoma gp100 蛋白 | 人 | – |
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| Melanoma gp100 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
1 reference - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our Premelanosome Protein 蛋白
: "BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 26, pp. 10658-63, (2013) (PubMed).
Aliases for Premelanosome Protein 蛋白
premelanosome protein (PMEL) 蛋白premelanosome protein (Pmel) 蛋白
premelanosome protein b (pmelb) 蛋白
premelanosome protein a (pmela) 蛋白
cb397 蛋白
D10H12S53E 蛋白
D12S53E 蛋白
D12S53Eh 蛋白
fdv 蛋白
gp87 蛋白
gp100 蛋白
ME20 蛋白
ME20-M 蛋白
ME20M 蛋白
MMP115 蛋白
P1 蛋白
P100 蛋白
PMEL17 蛋白
Pmel17 蛋白
pmel17 蛋白
RPE1 蛋白
sb:cb397 蛋白
SI 蛋白
Si 蛋白
SIL 蛋白
SILV 蛋白
Silv 蛋白
silva 蛋白
silver 蛋白
silverb 蛋白
wu:fc11g11 蛋白
wu:fj24g11 蛋白
zgc:136622 蛋白
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