PPARD 抗体
(Peroxisome Proliferator-Activated Receptor delta (PPARD))
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PPARD 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PPARD 抗体 (AA 19-90) | 人 | 兔 Polyclonal |
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| PPARD 抗体 (AA 72-146) | 人 | 小鼠 Monoclonal |
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| PPARD 抗体 (AA 72-146) | 人 | 小鼠 Monoclonal |
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| PPARD 抗体 (N-Term) | 人, 小鼠, 大鼠, 兔, 猴 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 19-90
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- PCRP-PPARD-4C2
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 72-146
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- PCRP-PPARD-4C2
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 72-146
Primary Antibody
- WB (Western Blotting: 所列应用)
- EIA (Enzyme Immunoassay: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 兔, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-14, N-Term
Latest Publications for our PPARD 抗体
: "Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1." in: PLoS ONE, Vol. 12, Issue 8, pp. e0181052, (2017) (PubMed).
: "Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy)." in: Human molecular genetics, Vol. 25, Issue 11, pp. 2194-2207, (2016) (PubMed).
: "PPARβ/δ and γ in a rat model of Parkinson's disease: possible involvement in PD symptoms." in: Journal of cellular biochemistry, Vol. 116, Issue 5, pp. 844-55, (2015) (PubMed).
: "Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation." in: The Journal of biological chemistry, Vol. 290, Issue 51, pp. 30306-20, (2015) (PubMed).
: "PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting." in: PLoS ONE, Vol. 8, Issue 3, pp. e59726, (2013) (PubMed).
: "Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPAR? in the associated hypertrophy." in: Journal of proteomics, Vol. 75, Issue 6, pp. 1816-29, (2012) (PubMed).
: "Biological function and prognostic significance of peroxisome proliferator-activated receptor ? in rectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 11, pp. 3760-70, (2011) (PubMed).
: "Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats." in: American journal of physiology. Endocrinology and metabolism, Vol. 298, Issue 6, pp. E1140-9, (2010) (PubMed).
: "Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells." in: Oncogene, Vol. 29, Issue 4, pp. 516-26, (2010) (PubMed).
: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
: "Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy)." in: Human molecular genetics, Vol. 25, Issue 11, pp. 2194-2207, (2016) (PubMed).
: "PPARβ/δ and γ in a rat model of Parkinson's disease: possible involvement in PD symptoms." in: Journal of cellular biochemistry, Vol. 116, Issue 5, pp. 844-55, (2015) (PubMed).
: "Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation." in: The Journal of biological chemistry, Vol. 290, Issue 51, pp. 30306-20, (2015) (PubMed).
: "PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting." in: PLoS ONE, Vol. 8, Issue 3, pp. e59726, (2013) (PubMed).
: "Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPAR? in the associated hypertrophy." in: Journal of proteomics, Vol. 75, Issue 6, pp. 1816-29, (2012) (PubMed).
: "Biological function and prognostic significance of peroxisome proliferator-activated receptor ? in rectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 11, pp. 3760-70, (2011) (PubMed).
: "Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats." in: American journal of physiology. Endocrinology and metabolism, Vol. 298, Issue 6, pp. E1140-9, (2010) (PubMed).
: "Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells." in: Oncogene, Vol. 29, Issue 4, pp. 516-26, (2010) (PubMed).
: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
Aliases for PPARD 抗体
peroxisome proliferator activated receptor delta (PPARD) 抗体peroxisome proliferator activator receptor delta (Ppard) 抗体
peroxisome proliferator activated receptor delta S homeolog (ppard.S) 抗体
peroxisome proliferator activated receptor delta (ppard) 抗体
peroxisome proliferator-activated receptor delta (Ppard) 抗体
peroxisome proliferator activated receptor delta (Ppard) 抗体
FAAR 抗体
NR1C2 抗体
Nr1c2 抗体
NUC-1 抗体
NUC1 抗体
NUCI 抗体
NUCII 抗体
PPAR-beta 抗体
PPAR-D/B 抗体
PPAR-delta 抗体
PPARB 抗体
Pparb 抗体
pparb 抗体
Pparb/d 抗体
PPARBETA 抗体
ppard 抗体
PPARD 抗体
PPARdelta 抗体
PPAR[b] 抗体
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