POLR3C 抗体
(Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB- DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
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50 results
POLR3C
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Hamster, 猴
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Aliases for POLR3C 抗体
polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog (polr3c.S) 抗体RNA polymerase III subunit C (POLR3C) 抗体
polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C) 抗体
polymerase (RNA) III (DNA directed) polypeptide C (62kD) (polr3c) 抗体
polymerase (RNA) III (DNA directed) polypeptide C (Polr3c) 抗体
RNA polymerase III subunit C (Polr3c) 抗体
polymerase (RNA) III (DNA directed) polypeptide C (polr3c) 抗体
4933407E01Rik 抗体
rpc3 抗体
RPC3 抗体
rpc62 抗体
RPC62 抗体
zgc:56348 抗体
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