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POLR3C 抗体 (AA 1-270)

POLR3C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269459
发货至: 中国
  • 抗原 See all POLR3C 抗体
    POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-270
    适用
    • 47
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 43
    • 4
    克隆类型
    • 46
    • 1
    多克隆
    标记
    • 19
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR3C antibody is un-conjugated
    应用范围
    • 42
    • 21
    • 13
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    POLR3C Rabbit pAb
    序列
    MTQAEIKLCS LLLQEHFGEI VEKIGVHLIR TGSQPLRVIA HDTGTSLDQV KKALCVLVQH NLVSYQVHKR GVVEYEAQCS RVLRMLRYPR YIYTTKTLYS DTGELIVEEL LLNGKLTMSA VVKKVADRLT ETMEDGKTMD YAEVSNTFVR LADTHFVQRC PSVPTTENSD PGPPPPAPTL VINEKDMYLV PKLSLIGKGK RRRSSDEDAA GEPKAKRPKY TTDNKEPIPD DGIYWQANLD RFHQHFRDQA IVSAVANRMD QTSSEIVRTM
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human POLR3C (NP_006459.3).
    亚型
    IgG
    Top Product
    Discover our top product POLR3C Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
    别名
    POLR3C (POLR3C 产品)
    别名
    rpc3 antibody, rpc62 antibody, 4933407E01Rik antibody, RPC3 antibody, RPC62 antibody, zgc:56348 antibody, polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog antibody, RNA polymerase III subunit C antibody, polymerase (RNA) III (DNA directed) polypeptide C (62kD) antibody, polymerase (RNA) III (DNA directed) polypeptide C antibody, polr3c.S antibody, POLR3C antibody, polr3c antibody, Polr3c antibody
    背景
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs induce type I interferon and NF- Kappa-B through the RIG-I pathway. Preferentially binds single-stranded DNA (ssDNA in a sequence-independent manner.,POLR3C,RPC3,RPC62,Epigenetics & Nuclear Signaling,POLR3C
    分子量
    60kDa
    基因ID
    10623
    UniProt
    Q9BUI4
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