PKN1 抗体
(Protein Kinase N1 (PKN1))
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
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Latest Publications for our PKN1 抗体
: "Detecting protein-phospholipid interactions. Epidermal growth factor-induced activation of phospholipase D1b in situ." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22974-9, (2002) (PubMed).: "Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 15, pp. 11064-70, (2000) (PubMed).
: "Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family." in: European journal of biochemistry / FEBS, Vol. 227, Issue 1-2, pp. 344-51, (1995) (PubMed).
: "Activation of PKN, a novel 120-kDa protein kinase with leucine zipper-like sequences, by unsaturated fatty acids and by limited proteolysis." in: Biochemical and biophysical research communications, Vol. 204, Issue 1, pp. 348-56, (1994) (PubMed).
Aliases for PKN1 抗体
protein kinase N1 (PKN1) 抗体protein kinase N1 (Pkn1) 抗体
protein kinase N1b (pkn1b) 抗体
protein kinase N1 (pkn1) 抗体
Protein kinase N (Pkn) 抗体
3-2 抗体
CG2049 抗体
CG2055 抗体
CT6637 抗体
CT6660 抗体
DBK 抗体
Dmel\\CG2049 抗体
DPKN 抗体
Dpkn 抗体
dPKN 抗体
F730027O18Rik 抗体
l(2)06736 抗体
l(2)45Ca 抗体
PAK-1 抗体
PAK1 抗体
Pk45C 抗体
Pk?3 抗体
PKN 抗体
Pkn 抗体
PKN-ALPHA 抗体
PKN1 抗体
PRK1 抗体
PRK2 抗体
PRKCL1 抗体
Prkcl1 抗体
Stk3 抗体
v(2)rG232 抗体
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