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PKN1 产品

(Protein Kinase N1 (PKN1))

Categories

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Featured PKN1 Categories

PKN1 抗体

High quality antibodies with extensive validation data.

PKN1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PKN1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PKN1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IP, RNAi
Validations
  • (6)
Cat. No. ABIN562393
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (6)
Cat. No. ABIN5542353
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
Cat. No. ABIN1682293
Quantity 100 μg
Datasheet Datasheet

Recommended PKN1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958932
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116806
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116807
Quantity 96 tests
Datasheet Datasheet

Recommended PKN1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570662
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5570661
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315234
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PKN1 Products

Hughes, Larijani, Parker: "Detecting protein-phospholipid interactions. Epidermal growth factor-induced activation of phospholipase D1b in situ." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22974-9, (2002) (PubMed).

Flynn, Mellor, Casamassima, Parker: "Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 15, pp. 11064-70, (2000) (PubMed).

Palmer, Ridden, Parker: "Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family." in: European journal of biochemistry / FEBS, Vol. 227, Issue 1-2, pp. 344-51, (1995) (PubMed).

Mukai, Kitagawa, Shibata, Takanaga, Mori, Shimakawa, Miyahara, Hirao, Ono: "Activation of PKN, a novel 120-kDa protein kinase with leucine zipper-like sequences, by unsaturated fatty acids and by limited proteolysis." in: Biochemical and biophysical research communications, Vol. 204, Issue 1, pp. 348-56, (1994) (PubMed).

Synonyms and alternative names related to PKN1

protein kinase N1 (PKN1), protein kinase N1 (Pkn1), protein kinase N1b (pkn1b), protein kinase N1 (pkn1), Protein kinase N (Pkn), 3-2, CG2049, CG2055, CT6637, CT6660, DBK, Dmel\\CG2049, DPKN, Dpkn, dPKN, F730027O18Rik, l(2)06736, l(2)45Ca, PAK-1, PAK1, Pk45C, Pk?3, PKN, Pkn, PKN-ALPHA, PKN1, PRK1, PRK2, PRKCL1, Prkcl1, Stk3, v(2)rG232

Protein level used designations for PKN1

  • protease-activated kinase 1
  • protein kinase C-like 1
  • protein kinase C-like PKN
  • protein kinase C-related kinase 1
  • protein kinase PKN-alpha
  • protein-kinase C-related kinase 1
  • serine-threonine kinase N
  • serine-threonine protein kinase N
  • serine/threonine protein kinase N
  • serine/threonine-protein kinase N1
  • serine/threonine kinase 3
  • protein kinase N1
  • serine/threonine-protein kinase N1-like
  • protein kinase PKN
  • CG2049-PB
  • CG2049-PC
  • CG2049-PD
  • CG2049-PE
  • CG2049-PF
  • CG2049-PG
  • CG2049-PH
  • CG2049-PI
  • CG2049-PJ
  • CG2049-PK
  • CG2049-PL
  • CG2049-PM
  • Pkn-PB
  • Pkn-PC
  • Pkn-PD
  • Pkn-PE
  • Pkn-PF
  • Pkn-PG
  • Pkn-PH
  • Pkn-PI
  • Pkn-PJ
  • Pkn-PK
  • Pkn-PL
  • Pkn-PM
  • protein kinase N
  • protein kinase c related
  • protein kinase related to protein kinase N
  • protein kinase-like 45C
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