PKM2 抗体
(Pyruvate Kinase M2 (PKM2))
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011].
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129 results
PKM2
适用: 人
WB, IHC, FACS, ELISA, IF, IP
宿主: 兔
Monoclonal
7B27B2
unconjugated
Recombinant Antibody
Latest Publications for our PKM2 抗体
: "A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1α protein." in: PLoS pathogens, Vol. 14, Issue 8, pp. e1007259, (2019) (PubMed).: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).
: "PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer." in: Scientific reports, Vol. 7, Issue 1, pp. 2886, (2018) (PubMed).
: "A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells." in: International journal of molecular sciences, Vol. 18, Issue 1, (2017) (PubMed).
: "MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells." in: Oncotarget, Vol. 8, Issue 20, pp. 33064-33077, (2017) (PubMed).
: "Specific tumor-derived CCL2 mediated by pyruvate kinase M2 in colorectal cancer cells contributes to macrophage recruitment in tumor microenvironment." in: Tumour biology, Vol. 39, Issue 3, pp. 1010428317695962, (2017) (PubMed).
: "Enhanced aerobic glycolysis of nasopharyngeal carcinoma cells by Epstein-Barr virus latent membrane protein 1." in: Experimental cell research, Vol. 359, Issue 1, pp. 94-100, (2017) (PubMed).
: "MiR-133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle-splicer polypyrimidine tract-binding protein 1." in: Cancer science, Vol. 107, Issue 12, pp. 1767-1775, (2016) (PubMed).
: "Altered glycometabolism affects both clinical features and prognosis of triple-negative and neoadjuvant chemotherapy-treated breast cancer." in: Tumour biology, Vol. 37, Issue 6, pp. 8159-68, (2016) (PubMed).
: "GLUT3 and PKM2 regulate OCT4 expression and support the hypoxic culture of human embryonic stem cells." in: Scientific reports, Vol. 5, pp. 17500, (2015) (PubMed).
Aliases for PKM2 抗体
pyruvate kinase M1/2 (PKM) 抗体pyruvate kinase, muscle (Pkm) 抗体
pyruvate kinase, muscle (PKM) 抗体
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