PKLR 抗体
(Pyruvate Kinase, Liver and RBC (PKLR))
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our PKLR 抗体
: "Association of C-terminal region of phosphoglycerate mutase with glycolytic complex regulates energy production in cancer cells." in: Journal of cellular physiology, Vol. 227, Issue 6, pp. 2613-21, (2012) (PubMed).: "Proteomic analyses of transgenic LQT1 and LQT2 rabbit hearts elucidate an increase in expression and activity of energy producing enzymes." in: Journal of proteomics, Vol. 75, Issue 17, pp. 5254-65, (2012) (PubMed).
: "Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians." in: Diabetes, Vol. 51, Issue 9, pp. 2861-5, (2002) (PubMed).
: "Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia." in: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23807-14, (2002) (PubMed).
: "PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations." in: Human genetics, Vol. 110, Issue 6, pp. 532-44, (2002) (PubMed).
Aliases for PKLR 抗体
pyruvate kinase L/R (PKLR) 抗体pyruvate kinase, liver and RBC (Pklr) 抗体
pyruvate kinase L/R (pklr) 抗体
pyruvate kinase, liver and RBC L homeolog (pklr.L) 抗体
pyruvate kinase, liver and RBC (pklr) 抗体
pyruvate kinase, liver and RBC (PKLR) 抗体
pyruvate kinase liver and red blood cell (Pklr) 抗体
pyruvate kinase L/R (Pklr) 抗体
pyruvate kinase PKLR-like (LOC100621940) 抗体
Pk-1 抗体
PK1 抗体
pk1 抗体
Pk1 抗体
PKL 抗体
Pklg 抗体
PKLR 抗体
pklr 抗体
PKR 抗体
PKRL 抗体
R-PK 抗体
RPK 抗体
wu:fd15e01 抗体
wu:fi37e08 抗体
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