电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PIAS3 抗体

(Protein Inhibitor of Activated STAT, 3 (PIAS3))
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].

Active filters:

  • 抗原: PIAS3
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6814092
PIAS3 抗体 (Alexa Fluor 488) PIAS3 · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6830155
PIAS3 抗体 (Alexa Fluor 594) PIAS3 · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6336806
PIAS3 抗体 PIAS3 · Primary Antibody 人 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 1 mL
  • 20 μL
  • 50 μL
  • 100 μL
  • 200 μL
发货至: 中国
ABIN6870408
PIAS3 抗体 (Biotin) PIAS3 · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN500491
PIAS3 抗体 (C-Term) PIAS3 · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • EIA (Enzyme Immunoassay: 所列应用)
  • 100 μg
  • 100 μg
发货至: 中国
Primary Antibody
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 488
产品编号 ABIN6814092
Primary Antibody
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 594
产品编号 ABIN6830155
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
产品编号 ABIN6336806
Primary Antibody
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
产品编号 ABIN6870408
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • EIA (Enzyme Immunoassay: 所列应用)
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
C-Term
产品编号 ABIN500491

Latest Publications for our PIAS3 抗体

Castillo-Lluva, Tatham, Jones, Jaffray, Edmondson, Hay, Malliri: "SUMOylation of the GTPase Rac1 is required for optimal cell migration." in: Nature cell biology, Vol. 12, Issue 11, pp. 1078-85, (2010) (PubMed).

Spoden, Morandell, Ehehalt, Fiedler, Jansen-Dürr, Hermann, Zwerschke: "The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2." in: Journal of cellular biochemistry, Vol. 107, Issue 2, pp. 293-302, (2009) (PubMed).

Brantley, Nabors, Gillespie, Choi, Palmer, Harrison, Roarty, Benveniste: "Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 15, pp. 4694-704, (2008) (PubMed).

Iwasaki, Hailemariam, Tsuji: "PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element." in: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22335-43, (2007) (PubMed).

Wetzler, Brady, Tracy, Li, Donohue, OLoughlin, Cheng, Mortazavi, McDonald, Kunapuli, Wallace, Baer, Cowell, Baumann: "Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 22, pp. 6817-25, (2006) (PubMed).

Nojiri, Joh, Miura, Sakata, Nomura, Nakao, Sobue, Ohara, Asai, Ito: "ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3." in: Biochemical and biophysical research communications, Vol. 314, Issue 1, pp. 97-103, (2004) (PubMed).

Long, Wang, Matsuura, He, Liu: "Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 1, pp. 99-104, (2004) (PubMed).

Cheng, Zhang, Zhou, Marasco: "Down-regulation of SHP1 and up-regulation of negative regulators of JAK/STAT signaling in HTLV-1 transformed cell lines and freshly transformed human peripheral blood CD4+ T-cells." in: Leukemia research, Vol. 28, Issue 1, pp. 71-82, (2003) (PubMed).

Yamamoto, Sato, Sekine, Yumioka, Imoto, Junicho, Fuse, Matsuda: "Molecular interactions between STAT3 and protein inhibitor of activated STAT3, and androgen receptor." in: Biochemical and biophysical research communications, Vol. 306, Issue 2, pp. 610-5, (2003) (PubMed).

Ueki, Seki, Yano, Saito, Masuho, Muramatsu: "Isolation and chromosomal assignment of a human gene encoding protein inhibitor of activated STAT3 (PIAS3)." in: Journal of human genetics, Vol. 44, Issue 3, pp. 193-6, (1999) (PubMed).

Aliases for PIAS3 抗体

protein inhibitor of activated STAT 3 (PIAS3) 抗体
protein inhibitor of activated STAT 3 (pias3) 抗体
protein inhibitor of activated STAT 3 (Pias3) 抗体
protein inhibitor of activated STAT, 3 (Pias3) 抗体
protein inhibitor of activated STAT 3 L homeolog (pias3.L) 抗体
PIAS3 抗体
Pias3l 抗体
ZMIZ5 抗体
You are here: