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PIAS3 抗体 (C-Term)

PIAS3 适用: 人, 大鼠, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500491
发货至: 中国
  • 抗原 See all PIAS3 抗体
    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
    抗原表位
    • 5
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    C-Term
    适用
    • 33
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    • 15
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    • 5
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    • 3
    • 3
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    • 1
    人, 大鼠, 小鼠
    宿主
    • 30
    • 3
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 26
    • 1
    • 1
    • 1
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    This PIAS3 antibody is un-conjugated
    应用范围
    • 24
    • 15
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    PIAS3 antibody was raised against a 12 amino acid peptide near the carboxy terminus of human PIAS3.
    亚型
    IgG
    Top Product
    Discover our top product PIAS3 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
    别名
    PIAS3 (PIAS3 产品)
    别名
    PIAS3 antibody, Pias3l antibody, ZMIZ5 antibody, protein inhibitor of activated STAT 3 antibody, protein inhibitor of activated STAT, 3 antibody, protein inhibitor of activated STAT 3 L homeolog antibody, PIAS3 antibody, pias3 antibody, Pias3 antibody, pias3.L antibody
    背景
    The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS3. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS3 binds specifically to STAT3 following the stimulation of STAT3. Increased expression of PIAS3 has been observed in several human cancers, including lung, breast, and brain tumors, but not in anaplastic lymphoma kinase-positive T/null-cell lymphomas, indicating that PIAS3 plays multiple roles in different tissue and cell types.Synonyms: E3 SUMO-protein ligase PIAS3, Protein inhibitor of activated STAT protein 3
    基因ID
    10401
    NCBI登录号
    NP_006090
    UniProt
    Q9Y6X2
    途径
    JAK/STAT Signaling
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