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PHD1 抗体

(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011].

63 results

EGLN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7616434
 
EGLN2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal OTI7H3 unconjugated
产品编号 ABIN2720025
 
EGLN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2334278
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Flow Cytometry (FACS)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
  • 适用
    • Human
    • Mouse
    • Rat
    • Dog
    • Cow
    • Guinea Pig
    • Rabbit
    • Horse
    • Zebrafish (Danio rerio)
    • Monkey
    • Pig
    • Bat
    • Chicken
    • Sheep
    • Xenopus laevis
  • 论文引用
  • 图像
  • 仅无防腐剂
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 2G3
    • 7G8
    • ABD-5
    • OTI7H3
    • R01-7G1
    • RB22708
  • 抗原表位
    • AA 321-407
    • AA 194-221
    • AA 283-407
    • N-Term
    • C-Term
    • AA 96-123
    • Middle Region
    • AA 1-407
    • AA 1-408
    • AA 150-250
    • AA 167-407
    • AA 281-315
    • AA 58-107
    • AA 95-123
  • 标记
    • 非结合性
    • FITC
    • APC
    • Biotin
    • HRP
    • PE
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
  • 抗体亚型
    • IgG
    • Ig Fraction
    • IgG1
    • IgG2a
    • IgG2a kappa
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Aviva Systems Biology
    • Acris
    • Abcepta
    • Biomatik
    • Boster Bio
    • CUSABIO
    • Elabscience
    • OriGene
    • USBio

Latest Publications for our PHD1 抗体

Zhang, Peng, Dai, Gan, Nie, Wei, Hu, Guo: "Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells." in: Cancer letters, Vol. 390, pp. 11-20, (2017) (PubMed).

Chu, Jones: "Changes in Hypoxia-Inducible Factor-1 (HIF-1) and Regulatory Prolyl Hydroxylase (PHD) Enzymes Following Hypoxic-Ischemic Injury in the Neonatal Rat." in: Neurochemical research, Vol. 41, Issue 3, pp. 515-22, (2016) (PubMed).

Takada, Zhuang, Inuzuka, Zhang, Zurlo, Zhang, Zhang: "EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor." in: Oncotarget, Vol. 8, Issue 4, pp. 6787-6795, (2016) (PubMed).

Deschoemaeker, Di Conza, Lilla, Martín-Pérez, Mennerich, Boon, Hendrikx, Maddocks, Marx, Radhakrishnan, Prenen, Schneider, Myllyharju, Kietzmann, Vousden, Zanivan, Mazzone: "PHD1 regulates p53-mediated colorectal cancer chemoresistance." in: EMBO molecular medicine, Vol. 7, Issue 10, pp. 1350-65, (2015) (PubMed).

Högel, Miikkulainen, Bino, Jaakkola: "Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27." in: Molecular cancer, Vol. 14, pp. 143, (2015) (PubMed).

Zhang, Wang, Chen, Takada, Fan, Zheng, Wen, Liu, Wang, Pestell, Aird, Kaelin, Liu, Zhang: "EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer." in: The EMBO journal, Vol. 34, Issue 23, pp. 2953-70, (2015) (PubMed).

Zheng, Zhai, Koivunen, Shin, Lu, Liu, Geisen, Chakraborty, Moslehi, Smalley, Wei, Chen, Chen, Beres, Zhang, Tsao, Brenner, Zhang, Fan, DePinho, Paik, Gygi, Kaelin, Zhang: "Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase." in: Genes & development, Vol. 28, Issue 13, pp. 1429-44, (2014) (PubMed).

Yogev, Lagos, Enver, Boshoff: "Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells." in: PLoS pathogens, Vol. 10, Issue 9, pp. e1004400, (2014) (PubMed).

Tan, Prosser, Vanags, Monger, Ng, Bursill: "High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 1, pp. 206-17, (2014) (PubMed).

Rawluszko, Bujnicka, Horbacka, Krokowicz, Jagodziński: "Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer." in: BMC cancer, Vol. 13, pp. 526, (2014) (PubMed).

Aliases for PHD1 抗体

egl-9 family hypoxia-inducible factor 1 (egln1) 抗体
egl-9 family hypoxia inducible factor 2 (EGLN2) 抗体
Egl nine homolog 2 (egln2) 抗体
egl-9 family hypoxia-inducible factor 2 L homeolog (egln2.L) 抗体
egl-9 family hypoxia-inducible factor 2 (Egln2) 抗体
0610011A13Rik 抗体
C85656 抗体
egln2 抗体
EIT6 抗体
Hif-p4h-1 抗体
HIF-PH1 抗体
HIFPH1 抗体
HPH-1 抗体
HPH-3 抗体
Ier4 抗体
PHD-1 抗体
PHD1 抗体
Phd1 抗体
phd2 抗体
SM-20 抗体
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