PHC1 抗体
(Polyhomeotic-Like 1 (PHC1))
This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008].
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Latest Publications for our PHC1 抗体
: "Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis." in: Human molecular genetics, Vol. 22, Issue 11, pp. 2200-13, (2013) (PubMed).: "Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6238-47, (2013) (PubMed).
: "Polycomb complexes repress developmental regulators in murine embryonic stem cells." in: Nature, Vol. 441, Issue 7091, pp. 349-53, (2006) (PubMed).
: "Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase." in: Histochemistry and cell biology, Vol. 120, Issue 2, pp. 111-9, (2003) (PubMed).
Aliases for PHC1 抗体
polyhomeotic homolog 1 (Phc1) 抗体polyhomeotic homolog 1 (PHC1) 抗体
polyhomeotic-like 1 (Drosophila) (Phc1) 抗体
AW557034 抗体
Edr 抗体
EDR1 抗体
Edr1 抗体
HPH1 抗体
Mph1 抗体
Rae-28 抗体
RAE28 抗体
rae28 抗体
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