PHC1 抗体
Our Local Distributor
北京 101111
Quick Overview for PHC1 抗体 (ABIN2668352)
抗原
See all PHC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Phc1 antibody (mAb) (Clone 6-1-3)
-
纯化方法
- Protein G Chromatography
-
免疫原
- This Phc1 antibody was raised against a recombinant mouse Phc1 protein fragment.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1 μg/μL
-
缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
-
储存条件
- -20 °C
-
储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
有效期
- 24 months
-
-
-
: "Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6238-47, (2013) (PubMed).
: "Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase." in: Histochemistry and cell biology, Vol. 120, Issue 2, pp. 111-9, (2003) (PubMed).
-
-
- PHC1 (Polyhomeotic-Like 1 (PHC1))
-
别名
- Phc1
-
背景
- Phc1, polyhomeotic homolog 1 (also known as EDR1, early development regulatory protein 1) is a component of the polycomb group (PcG) multiprotein PRC1 complex. The PRC1 complex is required to maintain the stable repression of the Hox genes during development. This chromatin-associated protein complex acts via chromatin remodeling and histone modifications. Phc1 has been shown to interact with PHC2, BMI1, MAPKAPK2 and MCRS1.
-
分子量
- 150 kDa
-
基因ID
- 1911
-
NCBI登录号
- NP_001036088
抗原
-