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PHC1 抗体

Cited in 2+ publications. The 小鼠 单克隆 anti-PHC1 antibody (Clone 6-1-3) (ABIN2668352) specifically detects PHC1 in WB, IF, IP 和 ICC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN2668352
发货至: 中国
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Quick Overview for PHC1 抗体 (ABIN2668352)

抗原

See all PHC1 抗体
PHC1 (Polyhomeotic-Like 1 (PHC1))

适用

  • 43
  • 11
  • 10
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 38
  • 5
小鼠

克隆类型

  • 40
  • 3
单克隆

标记

  • 18
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PHC1 antibody is un-conjugated

应用范围

  • 15
  • 13
  • 13
  • 12
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

6-1-3
  • 原理

    Phc1 antibody (mAb) (Clone 6-1-3)

    纯化方法

    Protein G Chromatography

    免疫原

    This Phc1 antibody was raised against a recombinant mouse Phc1 protein fragment.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Lin, Shen, Li, Tang, Gu, Chen, Hu, Rice, Lu, Wu: "Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6238-47, (2013) (PubMed).

    Miyagishima, Isono, Fujimura, Iyo, Takihara, Masumoto, Vidal, Koseki: "Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase." in: Histochemistry and cell biology, Vol. 120, Issue 2, pp. 111-9, (2003) (PubMed).

  • 抗原

    PHC1 (Polyhomeotic-Like 1 (PHC1))

    别名

    Phc1

    背景

    Phc1, polyhomeotic homolog 1 (also known as EDR1, early development regulatory protein 1) is a component of the polycomb group (PcG) multiprotein PRC1 complex. The PRC1 complex is required to maintain the stable repression of the Hox genes during development. This chromatin-associated protein complex acts via chromatin remodeling and histone modifications. Phc1 has been shown to interact with PHC2, BMI1, MAPKAPK2 and MCRS1.

    分子量

    150 kDa

    基因ID

    1911

    NCBI登录号

    NP_001036088
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