Bone Morphogenetic Protein 10 (BMP10) (N-Term) Peptide
BMP10
适用: 大鼠
宿主: 合成
BP, WB
产品编号 ABIN973838
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Bone Morphogenetic Protein 10 (BMP10) (N-Term) Peptide (ABIN973838)
抗原
BMP10
(Bone Morphogenetic Protein 10 (BMP10))
宿主
大鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Bmp10 Antibody(ARP47031_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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背景
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Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
Alias Symbols: Bmp10
Protein Size: 421 -
分子量
- 48 kDa
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基因ID
- 500245
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NCBI登录号
- NM_001031824, NP_001026994
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UniProt
- Q4AEG6
抗原
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