Bone Morphogenetic Protein 10 (BMP10) Peptide
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北京 101111
Quick Overview for Bone Morphogenetic Protein 10 (BMP10) Peptide (ABIN939752)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of Bmp10 antibody,
Alternative Names: Bmp10 control peptide, Bmp10 antibody Blocking Peptide, Anti-Bmp10 Blocking Peptide, bone morphogenetic protein 10 Blocking Peptide, Bmp10 Blocking Peptide, Bmp10, Bmp-10, Bmp 10, Bmp-10 Blocking Peptide, Bmp 10 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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背景
- Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
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分子量
- 48 kDa
抗原
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