Bone Morphogenetic Protein 10 (BMP10) (C-Term) Peptide
BMP10
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all BMP10 products
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- GYEAYECRGV CNYPLAEHLT PTKHAIIQAL VHLKNSQKAS KACCVPTKLE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-BMP10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- 背景
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BMP10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. It acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
Alias Symbols: -
Protein Size: 424 - 分子量
- 46 kDa
- 基因ID
- 27302
- NCBI登录号
- NM_014482, NP_055297
- UniProt
- O95393
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