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抗Rat (Rattus) CDX2 抗体:
抗Human CDX2 抗体:
抗Mouse (Murine) CDX2 抗体:
Human Monoclonal CDX2 Primary Antibody for BI, WB - ABIN967663
Hinoi, Loda, Fearon: Silencing of CDX2 expression in colon cancer via a dominant repression pathway. in The Journal of biological chemistry 2003
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Human Polyclonal CDX2 Primary Antibody for IHC (p), IP - ABIN151575
Verzi, Hatzis, Sulahian, Philips, Schuijers, Shin, Freed, Lynch, Dang, Brown, Clevers, Liu, Shivdasani: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. in Proceedings of the National Academy of Sciences of the United States of America 2010
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Human Monoclonal CDX2 Primary Antibody for FACS, ELISA - ABIN1724921
Lee, Vogt, Hsiao, Osunkoya: CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules. in Tumour biology 2012
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Human Monoclonal CDX2 Primary Antibody for ELISA, WB - ABIN1724918
Liu, Zhang, Zhan, Brock, Herman, Guo: CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. in Cancer biology & therapy 2012
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Human Monoclonal CDX2 Primary Antibody for IHC (p), IHC - ABIN152122
Flisikowska, Merkl, Landmann, Eser, Rezaei, Cui, Kurome, Zakhartchenko, Kessler, Wieland, Rottmann, Schmid, Schneider, Kind, Wolf, Saur, Schnieke: A porcine model of familial adenomatous polyposis. in Gastroenterology 2012
Human Polyclonal CDX2 Primary Antibody for ELISA, WB - ABIN251330
Qualtrough, Hinoi, Fearon, Paraskeva: Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system. in Gut 2002
Human Monoclonal CDX2 Primary Antibody for ELISA, WB - ABIN560320
Zulueta, Caretti, Signorelli, Dallolio, Trinchera: Transcriptional control of the B3GALT5 gene by a retroviral promoter and methylation of distant regulatory elements. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014
Cow (Bovine) Polyclonal CDX2 Primary Antibody for WB - ABIN2777319
Saad, Cho, Silverman, Liu: Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma. in American journal of clinical pathology 2004
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These results provide evidence that CDX2 plays an essential role in functional trophectoderm formation during primate embryonic development.
The results of the present study show that a lack of CDX2 expression in metastatic colorectal cancer is an adverse prognostic feature and a potential negative predictor of the response to chemotherapy.
We may conclude that hTERT promotes GIM by up-regulating CDX2 via NF-kappaB (显示 NFKB1 抗体) signaling pathway.
Our work suggests that combination of the consensual CMS (显示 Cd2ap 抗体) classification and lack of CDX2 expression could be a useful marker to identify CMS4/CDX2-negative patients with a very poor prognosis
AMPK (显示 PRKAA1 抗体) enhances intestinal barrier function and epithelial differentiation via promoting CDX2 expression, which is partially mediated by altered histone modifications in the Cdx2 promoter.
Findings suggest that H. pylori infectionis a driving force of gastric cardia carcinogenesis by upregulating caudal (显示 CAD 抗体)-related homeobox (显示 Lbx1 抗体) transcription factor 2 (显示 HNF1B 抗体) (CDX2) and inducing inflammation.
Data show that a two-marker panel of p40 (显示 IL9 抗体) (DeltaNp63) and CDX2 is highly sensitive and specific.
our findings demonstrated that MDR1 (显示 TBC1D9 抗体) expression is regulated by CDX2 and is related to drug resistance in ovarian mucinous adenocarcinoma.
The data presented provide a novel insight into how CDX2 is implicated in the transcriptional regulation of LAMC2 (显示 LAMC2 抗体) in intestinal epithelial cells, a function that is impaired during mucosal inflammation where a high level of TNF-alpha (显示 TNF 抗体) is present.
Cytapheresis might induce CDX2 expression without affecting the cell proliferation, thus resulting in mucosal healing with goblet cell restoration.
SOX2 (显示 SOX2 抗体) expression induces a cellular stem cell state in human colorectal cancer (CRC (显示 CALR 抗体)) with a decreased expression of CDX2. Furthermore, a down-regulated expression of CDX2 results in a poor patient prognosis in CRC (显示 CALR 抗体).
Data show that SLC7A7 (显示 Slc7a7 抗体) is a CDX2 target gene, and that CDX2 binds directly to the SLC7A7 (显示 Slc7a7 抗体) promoter.
these results provide further insight into the functional diversity of CDX2 in early mammalian embryos.
showed novel molecular regulation of CDX2 on Oct4 (显示 POU5F1 抗体), and provided important clues for clarifying the mechanism of interaction between CDX2 and Oct4 (显示 POU5F1 抗体) in embryo of mammals other than mouse
CDX2(Null)/BRAF (显示 BRAF 抗体)(V600E) expression in adult mouse intestinal epithelium led to serrated morphology tumors (including carcinomas) and BRAF (显示 BRAF 抗体)(V600E) potently interacted with CDX2 silencing to alter gene expression. Like human serrated lesions, CDX2(Null)/BRAF (显示 BRAF 抗体)(V600E)-mutant epithelium expressed gastric markers.
including Wnt (显示 WNT2 抗体) and Fgf pathway components active in the axial progenitor niche. Our data demonstrate that integration of the Cdx (显示 CDX1 抗体)/Hox (显示 MSH2 抗体) and T Brachyury (显示 TBX1 抗体) transcriptional networks controls differential axial growth during vertebrate trunk elongation
A new organ culture system for adult murine oesophagus is described. Using this, Cdx2 and HNF4alpha (显示 HNF4A 抗体) were ectopically expressed by adenoviral infection. We demonstrate the expression of CDX2 and HNF4alpha (显示 HNF4A 抗体) in human biopsy samples.
Cdx (显示 CDX1 抗体) members interact with the SWI (显示 SMARCA1 抗体)-SNF (显示 SNRPA 抗体) complex and make direct contact with Brg1 (显示 SMARCA4 抗体), a catalytic member of SWI (显示 SMARCA1 抗体)-SNF (显示 SNRPA 抗体). Both Cdx2 and Brg1 (显示 SMARCA4 抗体) co-occupy a number of Cdx (显示 CDX1 抗体) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 and Brg1 (显示 SMARCA4 抗体) occupancy occurs coincident with chromatin remodeling at some of these loci.
The authors identify a Cdx2-responsive segment of HoxA, immediately 5' to the recently defined regulatory domain orchestrating initial transcription of the first Hox (显示 MSH2 抗体) gene.
Cdx1 (显示 CDX1 抗体)-Cdx2 double null mutants exhibited loss of primitive erythroblasts, aberrant vascular remodelling of the yolk sac (显示 ADCY10 抗体) and a block in hematopoietic differentiation from yolk sac (显示 ADCY10 抗体)-derived cells in culture.
this study shows that Aloe vera (显示 IGF2BP3 抗体) gel suppresses colitis-related colon carcinogenesis via increased expression of CDX-2, a tumor suppressor in colorectal cancer
Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 (显示 HOXB7 抗体) and Cdx2 in colon cancer cells.
CDX2 is required for proliferation and differentiation of intestinal stem cells. Direct CDX2 targets in ISCs (显示 NFS1 抗体) may be activated or repressed.
results thus indicate that CDX2 is not required for TE formation during bovine development; nevertheless, it is necessary for maintaining TE integrity.
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
caudal type homeobox 2
, caudal type homeobox transcription factor 2
, caudal type homeo box transcription factor 2
, homeobox protein CDX-2
, caudal-type homeobox protein 2
, caudal type homeo box 2
, caudal-type homeobox transcription factor 2