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CDX2 抗体

CDX2 适用: 人 IHC (f), ISt 宿主: 小鼠 Monoclonal CDX2-2214 unconjugated
产品编号 ABIN6939058
发货至: 中国
  • 抗原 See all CDX2 抗体
    CDX2 (Caudal Type Homeobox 2 (CDX2))
    适用
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    宿主
    • 90
    • 38
    • 3
    小鼠
    克隆类型
    • 84
    • 46
    单克隆
    标记
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    This CDX2 antibody is un-conjugated
    应用范围
    • 80
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    • 31
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunostaining (ISt)
    特异性
    The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
    交叉反应 (详细)
    Human,
    纯化方法
    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
    免疫原
    Recombinant human full-length CDX2 protein
    克隆位点
    CDX2-2214
    亚型
    IgG1
    Top Product
    Discover our top product CDX2 Primary Antibody
  • 应用备注

    Positive Control: HT29 cells. Colon Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    有效期
    24 months
  • 抗原
    CDX2 (Caudal Type Homeobox 2 (CDX2))
    别名
    CDX2 (CDX2 产品)
    别名
    CDX2 antibody, MGC130987 antibody, cdx3-like antibody, CDX-3 antibody, CDX3 antibody, CDX-2 antibody, Cdx-2 antibody, caudal type homeobox 2 antibody, caudal type homeobox 2 L homeolog antibody, caudal type homeo box 2 antibody, CDX2 antibody, cdx2.L antibody, Cdx2 antibody
    背景
    Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2,CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)
    Cellular localisation: Nuclear
    分子量
    40kDa
    基因ID
    1045, 174249
    UniProt
    Q99626
    途径
    Peptide Hormone Metabolism, Stem Cell Maintenance
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