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PEPCK 产品

(phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK))

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This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].

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Featured PEPCK Categories

PEPCK 抗体

High quality antibodies with extensive validation data.

PEPCK ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PEPCK 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PEPCK 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, FACS
Validations
  • (1)
  • (6)
Cat. No. ABIN185483
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (6)
Cat. No. ABIN2855891
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (7)
Cat. No. ABIN7193363
Quantity 0.1 mg
Datasheet Datasheet

Recommended PEPCK ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969272
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958539
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1147906
Quantity 96 tests
Datasheet Datasheet

Recommended PEPCK 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1314318
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7197336
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3085613
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PEPCK Products

Lv, Qiu, Wang, Liu, Xue, Yu, Song, Chen, Wang, Song: "A GTP-dependent Phosphoenolpyruvate Carboxykinase from Crassostrea gigas Involved in Immune Recognition." in: Developmental and comparative immunology, Vol. 77, pp. 318-329, (2018) (PubMed).

Kanno, Watanabe, Takahashi, Abe, Ohira: "Anti-phosphoenolpyruvate carboxykinase 2 antibody in patients with autoimmune hepatitis." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 44, Issue 9, pp. 1019-25, (2014) (PubMed).

Méndez-Lucas, Duarte, Sunny, Satapati, He, Fu, Bermúdez, Burgess, Perales: "PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis." in: Journal of hepatology, Vol. 59, Issue 1, pp. 105-13, (2013) (PubMed).

Idnurm: "Light sensing in Aspergillus fumigatus highlights the case for establishing new models for fungal photobiology." in: mBio, Vol. 4, Issue 3, pp. e00260-13, (2013) (PubMed).

Zhou, Li, Qi, Zhang, Zhang, Wu, Hu, Wu, Liu, Yan, Jing, Liu, Zhai: "Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity." in: Diabetologia, Vol. 55, Issue 7, pp. 2032-43, (2012) (PubMed).

Duplus, Benelli, Reis, Fouque, Velho, Forest: "Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue: induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes." in: Biochimie, Vol. 85, Issue 12, pp. 1257-64, (2004) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Synonyms and alternative names related to PEPCK

phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2), phosphoenolpyruvate carboxykinase 2 (mitochondrial) (Pck2), phosphoenolpyruvate carboxykinase 2 (mitochondrial) (pck2), phosphoenolpyruvate carboxykinase 2, mitochondrial (Pck2), phosphoenolpyruvate carboxykinase 2 (mitochondrial) L homeolog (pck2.L), 1810010O14Rik, 9130022B02Rik, id:ibd5157, pck, pck2, pck2.S, PEPCK, PEPCK-M, PEPCK2, zgc:77867

Protein level used designations for PEPCK

  • PEP carboxykinase
  • phosphoenolpyruvate carboxykinase [GTP], mitochondrial
  • phosphoenolpyruvate carboxylase
  • phosphopyruvate carboxylase
  • mitochondrial phosphoenolpyruvate carboxykinase 2
  • phosphoenolpyruvate carboxykinase 2 (mitochondrial) L homeolog
  • phosphoenolpyruvate carboxykinase 2 (mitochondrial) S homeolog
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