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PEDF 产品

(serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))

Categories

The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.[provided by RefSeq, Mar 2011].

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Featured PEDF Categories

PEDF 抗体

High quality antibodies with extensive validation data.

PEDF ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PEDF 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PEDF 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7434440
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
Cat. No. ABIN3022373
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, ICC, IF
Validations
  • (4)
Cat. No. ABIN6265012
Quantity 100 μL
Datasheet Datasheet

Recommended PEDF ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6959425
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6973389
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (1)
Cat. No. ABIN6959424
Quantity 96 tests
Datasheet Datasheet

Recommended PEDF 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275576
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275577
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5509380
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PEDF Products

Guo, Fu, Liu, Wang, Li, Gao, Li, Zhang: "Role of Pigment Epithelium-Derived Factor in Arsenic-Induced Vascular Endothelial Dysfunction in a Rat Model." in: Biological trace element research, Vol. 190, Issue 2, pp. 405-413, (2020) (PubMed).

Wang, Yang, Yang, Li, Tan, Wu, Zhang, Li, Hu, Deng, Yang, Gao, Li, Yang, Chen, Cai: "Pigment Epithelial-Derived Factor Deficiency Accelerates Atherosclerosis Development via Promoting Endothelial Fatty Acid Uptake in Mice With Hyperlipidemia." in: Journal of the American Heart Association, Vol. 8, Issue 22, pp. e013028, (2020) (PubMed).

Deng, Gui, Kim, Xie, Chen, Li, He, Chen, Chen, Luo, Lu, Xie, Churchill, Xu, Zhou, Wu, Yu, John, Hirayasu, Nguyen, Liu, Huang, Li, Deng, Tang, Sadek, Zhang, Huang, Zou, Chen, Zhu, Arase, Xia, Jiang et al.: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." in: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).

Zhang, Pan, Qiu, Wei, Li, Jiang, Zhuang, Liu, Zhang, Dong: "A novel modified physiologically relevant model for cardiac angiogenesis." in: Microvascular research, Vol. 114, pp. 84-91, (2018) (PubMed).

Li, Wang, Zhang, Ma, Zhu: "Correlation Between Pigment Epithelium-Derived Factor (PEDF) level and Degree of Coronary Angiography and Severity of Coronary Artery Disease in a Chinese Population." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 1751-1758, (2018) (PubMed).

Sadri, Saremi, Dänicke, Rehage, Mielenz, Hosseini, Sauerwein: "Lactation-related changes in tissue expression of PEDF in dairy cows." in: Domestic animal endocrinology, Vol. 64, pp. 93-101, (2018) (PubMed).

Di, Zhao, Qi, Zhang, Feng, Shi, Zhou: "VEGF-B promotes recovery of corneal innervations and trophic functions in diabetic mice." in: Scientific reports, Vol. 7, pp. 40582, (2017) (PubMed).

Yao, Zhang, Wang, Zhao, Sun, Zheng, Dong, Guo: "Pigment Epithelium-Derived Factor (PEDF) Protects Osteoblastic Cell Line from Glucocorticoid-Induced Apoptosis via PEDF-R." in: International journal of molecular sciences, Vol. 17, Issue 5, (2016) (PubMed).

Zhang, Wei, Jiang, Li, Cui, Pan, Zhuang, Sun, Liu, Zhang, Dong: "PEDF and 34-mer inhibit angiogenesis in the heart by inducing tip cells apoptosis via up-regulating PPAR-γ to increase surface FasL." in: Apoptosis : an international journal on programmed cell death, Vol. 21, Issue 1, pp. 60-8, (2016) (PubMed).

Şahin, Apaydın, Töz, Sivrikoz, Genç, Turan, Cengiz, Eskicioğlu et al.: "Comparison of the effects of letrozole and cabergoline on vascular permeability, ovarian diameter, ovarian tissue VEGF levels, and blood PEDF levels, in a rat model of ovarian hyperstimulation ..." in: Archives of gynecology and obstetrics, Vol. 293, Issue 5, pp. 1101-6, (2016) (PubMed).

Synonyms and alternative names related to PEDF

serpin family F member 1 (SERPINF1), serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (serpinf1), serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog (serpinf1.L), serpin family F member 1 (Serpinf1), serine (or cysteine) peptidase inhibitor, clade F, member 1 (Serpinf1), AI195227, Dmrs91, EPC-1, MGC82984, OI6, OI12, PEDF, Pedf, Pedfl, Sdf3, SERPINF1, zgc:92072

Protein level used designations for PEDF

  • cell proliferation-inducing gene 35 protein
  • pigment epithelium-derived factor
  • serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
  • serpin F1
  • alpha-2 antiplasmin
  • pigment epithelium derived factor
  • serpin peptidase inhibitor, clade F, member 1
  • serpin-F1
  • serine (or cysteine) proteinase inhibitor, clade F), member 1
  • serine (or cysteine) proteinase inhibitor, clade F, member 1
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
  • alpha-2 antiplasmin, pigment epithelium derived factor
  • pigment epithelium-derived factor-like
  • SDF-3
  • caspin
  • stromal cell derived factor 3
  • stromal cell-derived factor 3
  • serine (or cysteine) peptidase inhibitor, clade F, member 1
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