电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PEG10 产品

(Paternally Expressed 10 (PEG10))

Categories

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured PEG10 Categories

PEG10 抗体

High quality antibodies with extensive validation data.

PEG10 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PEG10 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PEG10 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN1681320
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC
Validations
  • (3)
  • (3)
Cat. No. ABIN969348
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN524962
Quantity 50 μg
Datasheet Datasheet

Recommended PEG10 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969163
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6225627
Quantity 96 tests
Datasheet Datasheet

Recommended PEG10 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314640
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135926
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094526
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PEG10 Products

Rotinen, You, Yang, Coetzee, Reis-Sobreiro, Huang, Huang, Pan, Yáñez, Hazelett, Chu, Steadman, Morrissey, Nelson, Corey, Chung, Freedland, Di Vizio, Garraway, Murali, Knudsen, Freeman: "ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis." in: Nature medicine, Vol. 24, Issue 12, pp. 1887-1898, (2019) (PubMed).

Uxa, Bernhart, Mages, Fischer, Kohler, Hoffmann, Stadler, Engeland, Müller: "DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation." in: Nucleic acids research, Vol. 47, Issue 17, pp. 9087-9103, (2019) (PubMed).

Peng, Zhu, Yin, Zhang, Wei, Liu, Liu, Gao, Jiang, Miao: "PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 30, (2017) (PubMed).

Shyu, Lee, Lu, Chen, Chien, Chen, Lin, Tsou, Chen, Hsieh, Huang: "miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma." in: Journal of translational medicine, Vol. 14, Issue 1, pp. 200, (2016) (PubMed).

Kochetov, Ahmad, Ivanisenko, Volkova, Kolchanov, Sarai: "uORFs, reinitiation and alternative translation start sites in human mRNAs." in: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).

Wang, Xiao, Hu, Chen, Liu, Hu: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." in: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).

Jie, Lang, Jian, Chaoqun, Dehua, Yi, Yanping, Luokun, Qiuping, Hui, Feili, Boquan, Youxin, Jinquan: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." in: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).

Synonyms and alternative names related to PEG10

paternally expressed 10 (PEG10), paternally expressed 10 (Peg10), AA407948, EDR, Edr, HB-1, Mar2, Mart2, MEF3L, MyEF-3, RGAG3

Protein level used designations for PEG10

  • MEF3 like 1
  • MEF3-like protein 1
  • embryonal carcinoma differentiation regulated
  • embryonal carcinoma differentiation-regulated protein
  • mammalian retrotransposon-derived protein 2
  • myelin expression factor 3-like protein 1
  • paternally expressed gene 10 protein
  • retrotransposon gag domain containing 3
  • retrotransposon gag domain-containing protein 3
  • retrotransposon-derived gag-like polyprotein
  • retrotransposon-derived protein PEG10
  • ty3/Gypsy-like protein
  • MyEF-3 like
  • embryonal carcinoma differentiation regulated protein
  • myelin expression factor 3
  • paternally expressed 10
  • LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10
  • retrotransposon-derived protein PEG10-like
You are here:
客服