PELI2 抗体
(Pellino Homolog 2 (Drosophila) (PELI2))
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation (By similarity).
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PELI2
适用: 人, 小鼠, 大鼠
WB, ELISA, FACS, IF, IHC (p)
宿主: 兔
Polyclonal
unconjugated
Aliases for PELI2 抗体
pellino 2 (Peli2) 抗体pellino E3 ubiquitin protein ligase family member 2 (PELI2) 抗体
AW047589 抗体
BB129927 抗体
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