PELI2 抗体 (AA 118-420)
The 兔 多克隆 anti-PELI2 antibody is suitable to detect PELI2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF, FACS 和 IHC (p).
产品编号 ABIN7870263
发货至:
中国
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Quick Overview for PELI2 抗体 (AA 118-420) (ABIN7870263)
抗原
See all PELI2 抗体
PELI2
(Pellino Homolog 2 (Drosophila) (PELI2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This PELI2 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 118-420
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原理
- Pellino 2 Antibody / PELI2
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids D118-D420) was used as the immunogen for the Pellino 2 antibody.
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亚型
- IgG
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anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 1-420) antibody
PELI2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 22-51), (N-Term) antibodyPELI2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Pellino 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Pellino 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
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别名
- Pellino 2
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背景
- Protein pellino homolog 2 is a protein that in humans is encoded by the PELI2 gene. PELI2 is a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. It is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. It mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. It may be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. And it can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.
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UniProt
- Q9HAT8
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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