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PDK4 抗体

(Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008].

Active filters:

  • 抗原: PDK4
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7809062
PDK4 抗体 PDK4 · Primary Antibody 人 兔 Polyclonal
  • 100 μg
发货至: 中国
ABIN6080991
PDK4 抗体 (AA 143-333) (FITC) PDK4 · Primary Antibody 人 兔 Polyclonal
  • ELISA (ELISA: 所列应用)
  • 100 μL
  • 20 μL
  • 50 μL
发货至: 中国
ABIN2332659
PDK4 抗体 (AA 1-412) PDK4 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 1A9
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN6912696
PDK4 抗体 (Alexa Fluor 680) PDK4 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6896633
PDK4 抗体 (Alexa Fluor 555) PDK4 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6848444
PDK4 抗体 (Alexa Fluor 647) PDK4 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6864507
PDK4 抗体 (Alexa Fluor 750) PDK4 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6824254
PDK4 抗体 (Alexa Fluor 488) PDK4 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6840317
PDK4 抗体 (Alexa Fluor 594) PDK4 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN8124179
PDK4 抗体 (AA 34-84) PDK4 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • 50 μL
发货至: 中国
ABIN8124178
PDK4 抗体 (AA 235-285) PDK4 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 50 μL
发货至: 中国
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
产品编号 ABIN7809062
Primary Antibody
  • ELISA (ELISA: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
FITC
抗体亚型
IgG
抗原表位
AA 143-333
产品编号 ABIN6080991
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • ELISA (ELISA: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
1A9
标记
unconjugated
抗体亚型
IgG2b kappa
抗原表位
AA 1-412
产品编号 ABIN2332659
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 680
产品编号 ABIN6912696
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 555
产品编号 ABIN6896633
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 647
产品编号 ABIN6848444
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 750
产品编号 ABIN6864507
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 488
产品编号 ABIN6824254
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 594
产品编号 ABIN6840317
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 34-84
产品编号 ABIN8124179
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 235-285
产品编号 ABIN8124178

Latest Publications for our PDK4 抗体

Sirait-Fischer, Olesch, Fink, Berkefeld, Huard, Schmid, Takeda, Brüne, Weigert: "Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model." in: Frontiers in oncology, Vol. 10, pp. 1771, (2020) (PubMed).

Strowitzki, Radhakrishnan, Pavicevic, Scheer, Kimmer, Ritter, Tuffs, Volz, Vondran, Harnoss, Klose, Schmidt, Schneider: "High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases." in: British journal of cancer, Vol. 120, Issue 7, pp. 675-688, (2019) (PubMed).

Zhu, Liu, Liao, Diao, Wu, Liao, Wang, Li, Zhang, Wang, Xie, Jiang, Xu, Zeng, Yang, Zhang: "Overexpression of lncRNA EPB41L4A-AS1 Induces Metabolic Reprogramming in Trophoblast Cells and Placenta Tissue of Miscarriage." in: Molecular therapy. Nucleic acids, Vol. 18, pp. 518-532, (2019) (PubMed).

Svensson, Dent, Tahvilian, Martins, Sathe, Ochala, Patel, Schenk: "Defining the contribution of skeletal muscle pyruvate dehydrogenase alpha 1 (Pdha1) to exercise performance and insulin action." in: American journal of physiology. Endocrinology and metabolism, (2018) (PubMed).

Necela, Axenfeld, Serie, Kachergus, Perez, Thompson, Norton: "The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC-derived cardiomyocytes." in: Clinical and translational medicine, Vol. 6, Issue 1, pp. 5, (2017) (PubMed).

Cole, Abd Jamil, Heather, Murray, Sutton, Slingo, Sebag-Montefiore, Tan, Aksentijević, Gildea, Stuckey, Yeoh, Carr, Evans, Aasum, Schofield, Ratcliffe, Neubauer, Robbins, Clarke: "On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 8, pp. 2684-97, (2017) (PubMed).

Zhang, Wu, Choiniere, Yang, Huang, Bennett, Wang: "Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9a." in: Toxicology and applied pharmacology, Vol. 304, pp. 42-7, (2017) (PubMed).

Zhang, Zhang, Geng, Yi, Huo, Talmon, Kim, Wang, Wang: "Transforming Growth Factor β Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer." in: The Journal of biological chemistry, Vol. 291, Issue 33, pp. 17405-16, (2017) (PubMed).

Li, Li, Hu, Lei, Xiong, Ji, Yin, Wei, Hu: "The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis." in: Oncogene, Vol. 36, Issue 7, pp. 989-998, (2017) (PubMed).

Trinidad, Whalley, Rowlinson, Delpuech, Dudley, Rooney, Critchlow: "Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells." in: Oncogene, Vol. 36, Issue 44, pp. 6164-6176, (2017) (PubMed).

Aliases for PDK4 抗体

pyruvate dehydrogenase kinase 4 (pdk4) 抗体
pyruvate dehydrogenase kinase 4 (PDK4) 抗体
pyruvate dehydrogenase kinase, isoenzyme 4 (Pdk4) 抗体
pyruvate dehydrogenase kinase 4 (Pdk4) 抗体
AV005916 抗体
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