(phosphodiesterase 4D Interacting Protein (PDE4DIP))
The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010].
Roubin, Acquaviva, Chevrier, Sedjaï, Zyss, Birnbaum, Rosnet: "Myomegalin is necessary for the formation of centrosomal and Golgi-derived microtubules." in: Biology open, Vol. 2, Issue 2, pp. 238-50, (2013) (PubMed).
Overlack, Kilic, Bauss, Märker, Kremer, van Wijk, Wolfrum: "Direct interaction of the Usher syndrome 1G protein SANS and myomegalin in the retina." in: Biochimica et biophysica acta, Vol. 1813, Issue 10, pp. 1883-92, (2011) (PubMed).