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PDE4C 抗体

(phosphodiesterase 4C, CAMP-Specific (PDE4C))
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].

29 results

PDE4C 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7296540
 
PDE4C 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789817
 
PDE4C 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, IP, ICC, CM 宿主: 兔 Polyclonal unconjugated
Pubmed 9 references
产品编号 ABIN2750931
 
PDE4C 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1451109
 
PDE4C 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, IP, ICC, CM 宿主: 兔 Polyclonal Biotin
产品编号 ABIN5558816
 
PDE4C 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, IP, ICC, CM 宿主: 兔 Polyclonal FITC
产品编号 ABIN2750932
 
PDE4C 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1886372
 
PDE4C 适用: 人 WB, IHC (fp) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2800109
 
PDE4C 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2332219
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Confocal Microscopy (CM)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 适用
    • Human
    • Mouse
    • Rat
    • Dog
    • Bat
    • Cow
    • Guinea Pig
    • Horse
    • Pig
    • Rabbit
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 4E5
    • 6A10
    • RB38609
  • 抗原表位
    • AA 5-31
    • Internal Region
    • AA 1-99
    • C-Term
    • Center
    • N-Term
    • AA 260-340
    • AA 274-323
    • AA 291-340
    • AA 316-635
    • AA 325-637
    • AA 325-667
    • AA 333-378
    • AA 4-31
    • AA 457-506
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • APC
    • HRP
    • PE
  • 抗体亚型
    • IgG
    • Ig Fraction
    • IgG1 kappa
    • IgG3
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • FabGennix
    • Abcepta
    • Assay Biotechnology Company, Inc.
    • Aviva Systems Biology
    • Cohesion Biosciences
    • RayBiotech
    • Signalway
    • USBio

Latest Publications for our PDE4C 抗体

Cheng, Wu, He, Liu, Jia, Di, Ji: "siRNA-mediated silencing of phosphodiesterase 4B expression affects the production of cytokines in endotoxin-stimulated primary cultured microglia." in: Experimental and therapeutic medicine, Vol. 12, Issue 4, pp. 2257-2264, (2017) (PubMed).

Ji, Di, He, Liu, Liu, Li, Zhang: "Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation." in: Molecular medicine reports, Vol. 13, Issue 2, pp. 1914-22, (2016) (PubMed).

Massimi, Cardarelli, Galli, Giardi, Ragusa, Panera, Cinque, Cifone, Biagioni, Giorgi: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Yougbaré, Boire, Roy, Lugnier, Rouseau: "NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 5, pp. 353-61, (2014) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Yougbare, Morin, Senouvo, Sirois, Albadine, Lugnier, Rousseau: "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 301, Issue 4, pp. L441-50, (2011) (PubMed).

Murray, Patel, Suda, Zhang, Thistlethwaite, Yuan, Insel: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).

Gallagher, Bacon, Odumeru, Gallagher, Fitzpatrick, Regan: "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." in: Neurotoxicology and teratology, Vol. 26, Issue 1, pp. 73-81, (2004) (PubMed).

Aliases for PDE4C 抗体

phosphodiesterase 4C (PDE4C) 抗体
phosphodiesterase 4C, cAMP-specific a (pde4ca) 抗体
phosphodiesterase 4C (pde4c) 抗体
phosphodiesterase 4C, cAMP specific (Pde4c) 抗体
phosphodiesterase 4C (Pde4c) 抗体
dpde1 抗体
Dpde1 抗体
DPDE1 抗体
dunce 抗体
E130301F19Rik 抗体
im:7160317 抗体
pde4c 抗体
PDE4C 抗体
si:dkey-149i17.5 抗体
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