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PD-L1 蛋白

(CD274 (PD-L1))
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

84 results

PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % (SDS-PAGE)
产品编号 ABIN6253363
 
PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
产品编号 ABIN7519765
 
PD-L1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
产品编号 ABIN7534817
 
PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7597264
 
PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7597263
 
PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7597400
 
PD-L1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN4371704
 
PD-L1 宿主: 犬 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7597224
 
PD-L1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant SDS, WB, ELISA
产品编号 ABIN7575719
 
PD-L1 宿主: 小鼠 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, ELISA, Imm, AcA Active
产品编号 ABIN7607706
 
PD-L1 宿主: 人 宿主: Mammalian Cells Recombinant SDS, WB, ELISA
产品编号 ABIN7575718
 
PD-L1 宿主: 人 宿主: Mammalian Cells Recombinant SDS, WB, ELISA
产品编号 ABIN7575717
 
PD-L1 宿主: 小鼠 宿主: Mammalian Cells Recombinant SDS, WB, ELISA
产品编号 ABIN7580479
 
PD-L1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC
产品编号 ABIN7392077
 
PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7194771
 
PD-L1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
产品编号 ABIN7535911
 
PD-L1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC
产品编号 ABIN7392080
 
PD-L1 宿主: 人 宿主: 小麦胚 Recombinant AP
产品编号 ABIN1329970
 
PD-L1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % SDS, WB, Imm, PC
产品编号 ABIN7411294
 
PD-L1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC
产品编号 ABIN7416331
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Production (AbP)
    • Mass Spectrometry (MS)
    • Standard (STD)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Protein Interaction (PI)
  • 适用
    • Human
    • Mouse
    • Cynomolgus
    • Rhesus Monkey
    • Dog
    • Rat
    • Rabbit
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Human Cells
    • Mammalian Cells
    • CHO Cells
    • Wheat germ
    • Baculovirus infected Insect Cells
    • HEK-293T Cells
    • Insect cells (Sf9)
  • 抗原表位
    • AA 19-238
    • AA 19-239
    • AA 19-237
    • AA 18-238
    • AA 19-134
    • AA 34-241
    • partial
    • AA 1-238
    • AA 1-239
    • AA 128-238
    • AA 141-240
    • AA 19-132
    • AA 19-226
    • AA 24-234
    • AA 48-290
  • 标记
    • His tag
    • Fc Tag
    • 非结合性
    • DYKDDDDK Tag
    • Fc Tag,AVI tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • His tag,AVI tag,Biotin
    • His tag,Biotin
    • His-Avi Tag,Biotin
    • mFc Tag
    • DYKDDDDK-His Tag
    • Fc Tag,ECD
    • GST tag
    • His tag,Fc Tag,AVI tag,Biotin
    • His tag,GST tag
    • His-DYKDDDDK-Strep II Tag
    • Llama Fc Tag
    • Strep Tag
    • Twin-Strep tag
    • hIgG-His-tag
    • mFc-His Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • 生物活性
    • Biologically Active
  • Grade
    • MALS verified
    • HPLC verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • Cohesion Biosciences
    • OriGene
    • ProteoGenix

Latest Publications for our PD-L1 蛋白

Ye, Yuan, Yue, Rubin, Chen: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." in: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).

Li, Ren, Zhao, Lou: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." in: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Li, Course, McNeish, Drescher, Valdmanis, Lieber: "Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models." in: Cancer research, Vol. 80, Issue 3, pp. 549-560, (2020) (PubMed).

Lu, Xue, Deng, Zhou, Yu, Deng, Huang, Yi, Liang, Wang, Shen, Tong, Wang, Li, Song, Li, Su, Ding, Gong, Zhu, Wang, Zou, Zhang, Li, Zhou, Liu, Yu, Wang, Zhang, Yin, Xia, Zeng, Zhou, Ying, Chen, Wei, Li et al.: "Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. ..." in: Nature medicine, Vol. 26, Issue 5, pp. 732-740, (2020) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Tocheva, Lerrer, Mor: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).

Ganesan, Ahmed, Okoye, Arutyunova, Babu, Turnbull, Kundu, Shields, Agopsowicz, Xu, Tabana, Srivastava, Zhang, Moon, Belovodskiy, Hena, Kandadai, Hosseini, Hitt, Walker, Smylie, West, Siraki, Lemieux et al.: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).

Chen, Xu, Du, Hou, Fan, Wu, Yan: "Enhanced Expression of PD-L1 on Microglia After Surgical Brain Injury Exerts Self-Protection from Inflammation and Promotes Neurological Repair." in: Neurochemical research, Vol. 44, Issue 11, pp. 2470-2481, (2019) (PubMed).

Son, Park, Seo, Lee, Heo, Kim: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." in: Journal of drug targeting, pp. 1-9, (2019) (PubMed).

Aliases for PD-L1 蛋白

CD274 molecule (CD274) 蛋白
CD274 antigen (Cd274) 蛋白
programmed cell death 1 ligand 2 (PDCD1LG2) 蛋白
CD274 molecule (Cd274) 蛋白
A530045L16Rik 蛋白
B7-H 蛋白
B7H1 蛋白
B7h1 蛋白
PD-L1 蛋白
PDCD1L1 蛋白
Pdcd1l1 蛋白
PDCD1LG1 蛋白
Pdcd1lg1 蛋白
PDL1 蛋白
Pdl1 蛋白
RGD1566211 蛋白
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