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PD-L1 蛋白

(CD274 (PD-L1))
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

98 results

PD-L1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
产品编号 ABIN5608343
100 μg
发货至: 中国
获取报价
 
PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
产品编号 ABIN2566857
25 μg
发货至: 中国
获取报价
 
PD-L1 宿主: 小鼠 宿主: Bacteria Recombinant
产品编号 ABIN7819829
 
PD-L1 宿主: Treeshrew (Tupaia) 宿主: Eukaryota Recombinant
产品编号 ABIN7820535
 
PD-L1 宿主: Treeshrew (Tupaia) 宿主: Eukaryota Recombinant
产品编号 ABIN7820534
 
PD-L1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892207
1 mg
发货至: 中国
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PD-L1 宿主: 人 宿主: Mammalian Cells Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892208
1 mg
发货至: 中国
获取报价
 
PD-L1 宿主: 小鼠 宿主: Mammalian Cells Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892209
1 mg
发货至: 中国
获取报价
 
PD-L1 宿主: Treeshrew (Tupaia) 宿主: Mammalian Cells Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892214
1 mg
发货至: 中国
获取报价
 
PD-L1 宿主: Treeshrew (Tupaia) 宿主: Mammalian Cells Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892215
1 mg
发货至: 中国
获取报价
 
PD-L1 宿主: 人 宿主: Mammalian Cells Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892211
1 mg
发货至: 中国
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PD-L1 宿主: 犬 宿主: Mammalian Cells Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892210
1 mg
发货至: 中国
获取报价
 
PD-L1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892213
1 mg
发货至: 中国
获取报价
 
PD-L1 宿主: Cat 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA, Imm
产品编号 ABIN7892212
1 mg
发货至: 中国
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PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7866540
50 μg
发货至: 中国
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PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7866539
50 μg
发货至: 中国
获取报价
 
PD-L1 宿主: 犬 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7866538
50 μg
发货至: 中国
获取报价
 
PD-L1 宿主: 犬 宿主: Mammalian Cells 90 % Func
产品编号 ABIN4948846
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Affinity Measurement (AM)
    • Immunoassay (IA)
    • Screening Assay (ScA)
    • Antibody Drug Assay (ADA)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Production (AbP)
    • Standard (STD)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Mass Spectrometry (MS)
    • Protein Interaction (PI)
  • 适用
    • Human
    • Mouse
    • Cynomolgus
    • Dog
    • Rhesus Monkey
    • Rat
    • Treeshrew (Tupaia)
    • Cat
    • Rabbit
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Human Cells
    • Mammalian Cells
    • Bacteria
    • Eukaryota
    • Wheat germ
    • Baculovirus infected Insect Cells
    • CHO Cells
    • HEK-293T Cells
    • Insect cells (Sf9)
  • 抗原表位
    • AA 19-238
    • AA 19-239
    • AA 99-330
    • AA 128-238
    • AA 19-132
    • AA 1-239
    • AA 18-238
    • AA 19-134
    • AA 19-236
    • AA 19-237
    • AA 34-241
    • partial
    • AA 1-238
    • AA 141-240
    • AA 19-226
    • AA 24-234
    • AA 48-290
  • 标记
    • His tag
    • Fc Tag
    • 非结合性
    • hFc Tag
    • mFc Tag
    • DYKDDDDK Tag
    • Biotin,His tag
    • Fc Tag,AVI tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • His tag,AVI tag,Biotin
    • His-Avi Tag,Biotin
    • Biotin,His-Avi Tag
    • DYKDDDDK-His Tag
    • Fc Tag,ECD
    • GST tag
    • His tag,Fc Tag,AVI tag,Biotin
    • His tag,GST tag
    • His tag,mFc Tag
    • His-DYKDDDDK-Strep II Tag
    • His-IF2DI Tag
    • Llama Fc Tag
    • SUMO Tag
    • Strep Tag
    • Twin-Strep tag
    • hIgG-His-tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • 生物活性
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • Signalway
    • Abeomics
    • ProteoGenix
    • ProSci
    • OriGene
    • Cohesion Biosciences

Latest Publications for our PD-L1 蛋白

Ye, Yuan, Yue, Rubin, Chen: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." in: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).

Li, Ren, Zhao, Lou: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." in: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Li, Course, McNeish, Drescher, Valdmanis, Lieber: "Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models." in: Cancer research, Vol. 80, Issue 3, pp. 549-560, (2020) (PubMed).

Lu, Xue, Deng, Zhou, Yu, Deng, Huang, Yi, Liang, Wang, Shen, Tong, Wang, Li, Song, Li, Su, Ding, Gong, Zhu, Wang, Zou, Zhang, Li, Zhou, Liu, Yu, Wang, Zhang, Yin, Xia, Zeng, Zhou, Ying, Chen, Wei, Li et al.: "Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. ..." in: Nature medicine, Vol. 26, Issue 5, pp. 732-740, (2020) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Tocheva, Lerrer, Mor: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).

Ganesan, Ahmed, Okoye, Arutyunova, Babu, Turnbull, Kundu, Shields, Agopsowicz, Xu, Tabana, Srivastava, Zhang, Moon, Belovodskiy, Hena, Kandadai, Hosseini, Hitt, Walker, Smylie, West, Siraki, Lemieux et al.: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).

Chen, Xu, Du, Hou, Fan, Wu, Yan: "Enhanced Expression of PD-L1 on Microglia After Surgical Brain Injury Exerts Self-Protection from Inflammation and Promotes Neurological Repair." in: Neurochemical research, Vol. 44, Issue 11, pp. 2470-2481, (2019) (PubMed).

Son, Park, Seo, Lee, Heo, Kim: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." in: Journal of drug targeting, pp. 1-9, (2019) (PubMed).

Aliases for PD-L1 蛋白

CD274 molecule (CD274) 蛋白
CD274 antigen (Cd274) 蛋白
programmed cell death 1 ligand 2 (PDCD1LG2) 蛋白
CD274 molecule (Cd274) 蛋白
A530045L16Rik 蛋白
B7-H 蛋白
B7H1 蛋白
B7h1 蛋白
PD-L1 蛋白
PDCD1L1 蛋白
Pdcd1l1 蛋白
PDCD1LG1 蛋白
Pdcd1lg1 蛋白
PDL1 蛋白
Pdl1 蛋白
RGD1566211 蛋白
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