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PD-L1 蛋白

(CD274 (PD-L1))
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

82 results

PD-L1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
产品编号 ABIN7122198
50 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
产品编号 ABIN7122197
50 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: Cynomolgus 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7538168
50 μg
发货至: 中国
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PD-L1 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7320974
50 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320750
50 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN2181635
100 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN2870578
200 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6810006
1 mg (More quantities available)
发货至: 中国
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PD-L1 宿主: Cynomolgus, 猕猴 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN2181633
100 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN7013168
100 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7416331
100 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % WB, SDS, Imm, PC
产品编号 ABIN7411294
100 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 大鼠 宿主: Mammalian Cells Recombinant Greater than 95 % as determined by SDS-PAGE. WB, ELISA
产品编号 ABIN7704246
50 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7392080
100 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7392077
100 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 人 宿主: 小麦胚 Recombinant AP
产品编号 ABIN1329970
 
PD-L1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % pure SDS
产品编号 ABIN2128424
20 μg
发货至: 中国
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PD-L1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % pure SDS
产品编号 ABIN2128425
100 μg
发货至: 中国
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PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505719
100 μg (More quantities available)
发货至: 中国
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PD-L1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505141
100 μg (More quantities available)
发货至: 中国
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  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Affinity Measurement (AM)
    • Immunoassay (IA)
    • Immunogen (Imm)
    • Screening Assay (ScA)
    • Antibody Drug Assay (ADA)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Production (AbP)
    • Standard (STD)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Mass Spectrometry (MS)
    • Protein Interaction (PI)
  • 适用
    • Human
    • Mouse
    • Cynomolgus
    • Rhesus Monkey
    • Dog
    • Rat
    • Treeshrew (Tupaia)
    • Cat
    • Rabbit
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Human Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • Bacteria
    • Eukaryota
    • Wheat germ
    • Baculovirus infected Insect Cells
    • CHO Cells
    • HEK-293T Cells
    • Insect cells (Sf9)
  • 抗原表位
    • AA 19-238
    • AA 19-239
    • AA 1-239
    • AA 18-238
    • AA 19-134
    • AA 19-236
    • AA 19-237
    • AA 34-241
    • partial
    • AA 1-238
    • AA 128-238
    • AA 141-240
    • AA 19-132
    • AA 19-226
    • AA 24-234
    • AA 48-290
  • 标记
    • His tag
    • Fc Tag
    • 非结合性
    • DYKDDDDK Tag
    • mFc Tag
    • Biotin,His tag
    • Fc Tag,AVI tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • His tag,AVI tag,Biotin
    • Biotin,His-Avi Tag
    • DYKDDDDK-His Tag
    • Fc Tag,ECD
    • GST tag
    • His tag,Fc Tag,AVI tag,Biotin
    • His tag,GST tag
    • His tag,mFc Tag
    • His-Avi Tag,Biotin
    • His-DYKDDDDK-Strep II Tag
    • His-IF2DI Tag
    • Llama Fc Tag
    • SUMO Tag
    • Strep Tag
    • Twin-Strep tag
    • hFc Tag
    • hIgG-His-tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • 生物活性
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • ProteoGenix
    • ProSci
    • OriGene
    • Abeomics
    • Cohesion Biosciences

Latest Publications for our PD-L1 蛋白

Ye, Yuan, Yue, Rubin, Chen: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." in: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).

Li, Ren, Zhao, Lou: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." in: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Li, Course, McNeish, Drescher, Valdmanis, Lieber: "Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models." in: Cancer research, Vol. 80, Issue 3, pp. 549-560, (2020) (PubMed).

Lu, Xue, Deng, Zhou, Yu, Deng, Huang, Yi, Liang, Wang, Shen, Tong, Wang, Li, Song, Li, Su, Ding, Gong, Zhu, Wang, Zou, Zhang, Li, Zhou, Liu, Yu, Wang, Zhang, Yin, Xia, Zeng, Zhou, Ying, Chen, Wei, Li et al.: "Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. ..." in: Nature medicine, Vol. 26, Issue 5, pp. 732-740, (2020) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Tocheva, Lerrer, Mor: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).

Ganesan, Ahmed, Okoye, Arutyunova, Babu, Turnbull, Kundu, Shields, Agopsowicz, Xu, Tabana, Srivastava, Zhang, Moon, Belovodskiy, Hena, Kandadai, Hosseini, Hitt, Walker, Smylie, West, Siraki, Lemieux et al.: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).

Chen, Xu, Du, Hou, Fan, Wu, Yan: "Enhanced Expression of PD-L1 on Microglia After Surgical Brain Injury Exerts Self-Protection from Inflammation and Promotes Neurological Repair." in: Neurochemical research, Vol. 44, Issue 11, pp. 2470-2481, (2019) (PubMed).

Son, Park, Seo, Lee, Heo, Kim: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." in: Journal of drug targeting, pp. 1-9, (2019) (PubMed).

Aliases for PD-L1 蛋白

CD274 molecule (CD274) 蛋白
CD274 antigen (Cd274) 蛋白
programmed cell death 1 ligand 2 (PDCD1LG2) 蛋白
CD274 molecule (Cd274) 蛋白
A530045L16Rik 蛋白
B7-H 蛋白
B7H1 蛋白
B7h1 蛋白
PD-L1 蛋白
PDCD1L1 蛋白
Pdcd1l1 蛋白
PDCD1LG1 蛋白
Pdcd1lg1 蛋白
PDL1 蛋白
Pdl1 蛋白
RGD1566211 蛋白
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