蛋白简介

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NFKB1

• nuclear factor kappa B subunit 1 (NFKB1) 抗体
• nuclear factor kappa B subunit 1 (Nfkb1) 抗体
• nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog (nfkb1.L) 抗体
• nuclear factor NF-kappa-B p105 subunit (CpipJ_CPIJ012236) 抗体
• nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Nfkb1) 抗体
• 显示所有的基因名称
• nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (nfkb1) 抗体

• BICDR-1 抗体
• bicdr1 抗体
• ccdc64 抗体
• ebp-1 抗体
• kbf1 抗体
• 显示所有的同义词和别名
• nf-kappa-b 抗体
• nf-kappaB 抗体
• NF-kappaB1 抗体
• NF-kB 抗体
• NF-KB1 抗体
• NFkappaB 抗体
• nfkb-p50 抗体
• nfkb-p105 抗体
• p50 抗体
• p50/p105 抗体
• p105 抗体

Protein level used designations for NFKB1

DNA binding factor KBF1 , DNA-binding factor KBF1 , NF-kappabeta , nuclear factor NF-kappa-B p105 subunit , nuclear factor NF-kappa-B p50 subunit , nuclear factor kappa-B DNA binding subunit , nuclear factor of kappa light chain gene enhancer in B-cells 1, p105 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 , NF-kB p50 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) , nuclear factor kappa-B, subunit 1 , nuclear factor of kappa light polypeptide enhancer in B-cells 1 , nuclear factor kappa-B 1 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 , nuclear factor NF-kappa-B p105 subunit-like , EBP-1 , NF kappaB1 , NF-kappa-B1 p84/NF-kappa-B1 p98 , NF-kappaB p50 , nuclear factor kappaB p50 , nuclear factor-kappaB p50 , p50 subunit of NF kappaB , p50 subunit of NF-kappaB , BICD-related protein 1 , NF-kB1 precursor protein , bicaudal D-related protein 1 , coiled-coil domain-containing protein 64A , p50