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抗Human FAS 抗体:
抗Mouse (Murine) FAS 抗体:
抗Rat (Rattus) FAS 抗体:
Mouse (Murine) Polyclonal FAS Primary Antibody for IHC (fro), IHC (p) - ABIN3044338
Jiang, Li, Zhou, Wang, Zhang, Wang: Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways. in International journal of molecular medicine 2014
Show all 14 Pubmed References
Rat (Rattus) Polyclonal FAS Primary Antibody for WB - ABIN3042386
Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013
Show all 13 Pubmed References
Human Polyclonal FAS Primary Antibody for IHC (p), WB - ABIN3042387
Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015
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Human Monoclonal FAS Primary Antibody for IHC (fro), IF - ABIN1106610
Vega, Jazirehi, Huerta-Yepez, Bonavida: Rituximab-induced inhibition of YY1 and Bcl-xL expression in Ramos non-Hodgkin's lymphoma cell line via inhibition of NF-kappa B activity: role of YY1 and Bcl-xL in Fas resistance and chemoresistance, respectively. in Journal of immunology (Baltimore, Md. : 1950) 2005
Show all 16 Pubmed References
Human Monoclonal FAS Primary Antibody for FACS - ABIN5541252
Hata, Matsuzaki, Takeya, Yoshida, Sonoki, Nagasaki, Kuribayashi, Kawano, Takatsuki: Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders. in Blood 1995
Show all 12 Pubmed References
Human Monoclonal FAS Primary Antibody for FACS - ABIN5541251
Boirivant, Pica, DeMaria, Testi, Pallone, Strober: Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis. in The Journal of clinical investigation 1997
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Mouse (Murine) Monoclonal FAS Primary Antibody for CyTox, FACS - ABIN1177304
Enari, Hug, Nagata: Involvement of an ICE-like protease in Fas-mediated apoptosis. in Nature 1995
Show all 9 Pubmed References
Mouse (Murine) Monoclonal FAS Primary Antibody for FACS - ABIN2689463
Hiromatsu, Aoki, Makino, Matsumoto, Mizuochi, Gotoh, Nomoto, Ogasawara, Nagata, Yoshikai: Increased Fas antigen expression in murine retrovirus-induced immunodeficiency syndrome, MAIDS. in European journal of immunology 1994
Show all 9 Pubmed References
Mouse (Murine) Monoclonal FAS Primary Antibody for CyTox, FACS - ABIN2689461
Kägi, Vignaux, Ledermann, Bürki, Depraetere, Nagata, Hengartner, Golstein: Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. in Science (New York, N.Y.) 1994
Show all 5 Pubmed References
Human Polyclonal FAS Primary Antibody for IHC, IHC (p) - ABIN448412
Horuz, Göktaş, Çetinel, Akça, Aydın, Ekici, Albayrak, Sarıca: Role of TNF-associated cytokines in renal tubular cell apoptosis induced by hyperoxaluria. in Urolithiasis 2013
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Complete local landscape for a defined molecular function-the alternative splicing of an exon (FAS/CD95 exon 6). The extensive epistasis in the landscape predicts that exonic regulatory sequences may diverge between species even when exon inclusion levels are functionally important and conserved by selection.
Paper analyses results of serum cytokines and lymphocyte apoptosis study in nodular goiter against the background of autoimmune thyroiditis and thyroid adenoma based on the cell preparedness to apoptosis, the number of apoptotic lymphocytes and the content of proapoptotic tumor necrosis factor-alpha, interleukins in serum, considering the polymorphism of BCL-2, CTLA-4 and APO-1 genes.
These results demonstrated that overexpression of ING4 (显示 ING4 抗体) can induce the apoptosis of melanoma cells and CD3 (显示 CD3 抗体)+ T cells through signaling pathways such as the Fas/FasL (显示 FASL 抗体) pathway, and that ING4 (显示 ING4 抗体) gene therapy for melanoma treatment is a novel approach.
Tag7 (显示 PGLYRP1 抗体) activates lymphocytes capable of Fasl (显示 FASL 抗体)-Fas-dependent contact killing of virus-infected cells.
These results indicated that cMyc (显示 MYC 抗体) and Fas regulated the sensitivity of A549 cells to irradiation by regulating caspase8-mediated Bid (显示 BID 抗体) activation and the subsequent association with the mitochondrial pathway of apoptosis.
this study characterized in juvenile systemic lupus erythematosus a distinct profile from adult SLE that comprises increased sFas, sTRAIL, and reduced sFasL (显示 FASL 抗体), notably in patients with active disease and with nephritis.
results from the current study showed that the association of FAS-670A/G SNP with idiopathic azoospermia was not found in a population of men with idiopathic infertility.
The Btk (显示 BTK 抗体)-dependent PIP5K1gamma lipid kinase activation by Fas counteracts FasL (显示 FASL 抗体)-induced cell death.
Study identify genes highly expressed in Kras knockout lung cancer cells, including the Fas receptor gene. Antibodies that activate Fas receptor selectively induced apoptosis in Kras-independent lung cancer cells suggesting that FAS is involved in KRAS-related drug resistance.
The authors observed differential expression of CD95(Fas) in CD27 (显示 CD27 抗体)(+) B-cells from cirrhotic patients that was inversely correlated with peripheral CD27 (显示 CD27 抗体)(+) B-cell frequency. They conclude that peripheral CD27 (显示 CD27 抗体)(+) memory B-cells in cirrhosis exhibit increased sensitivity to Fas-induced apoptosis in an activation-dependent manner to which endotoxin contributes, associated with reduced frequency of circulating memory B-cells.
Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (显示 PTGES 抗体)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF (显示 TNF 抗体)) and Fas were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.
Results did not support that K8/K18 (显示 KRT18 抗体) filaments influence the expression of Fas on the surface of luteal cells.
activation of the Fas pathway and presence of FSH (显示 BRD2 抗体) during in vitro maturation increased the incidence of apoptosis in cumulus cells
demonstrated for the first time that normal ejaculated spermatozoa express Fas antigen (显示 FASL 抗体); data showed that a large percentage of normal ejaculated spermatozoa of fertile bulls are immunocytochemically positive for Fas
identification of 14-3-3zeta (显示 YWHAZ 抗体) as a novel phosphocofilin binding protein involved in the maintenance of the cellular phosphocofilin pool
Findings indicate that induction of apoptosis through Fas is dependent on receptor palmitoylation in primary immune cells, and Fas may prevent autoimmunity by mechanisms other than inducing apoptosis.
Both Sharpin (显示 SHARPIN 抗体)/Fas and Sharpin (显示 SHARPIN 抗体)/Fasl (显示 FASL 抗体) compound mutant mice developed an auto-inflammatory phenotype similar to that seen in Sharpin (显示 SHARPIN 抗体) null mice, indicating that initiation of apoptosis by FAS signalling is likely not involved in the pathogenesis of this disease.
leucine deprivation induces the expression of miR (显示 MLXIP 抗体)-212-5p in a GCN2 (显示 EIF2AK4 抗体)/ATF4 (显示 ATF4 抗体)-dependent manner. miR (显示 MLXIP 抗体)-212-5p suppresses lipid accumulation in liver by targeting FAS and SCD1 (显示 SCD 抗体) under both normal diet and high-fat diet conditions.
Our data show that loss of Fas activity strongly affects the early development of atopic dermatitis (AD) by leading to Th2-dominant inflammation characterized by dermal infiltration of CD4 (显示 CD4 抗体)+ T cells, neutrophils and increased skin expression of Th2 cytokines.However, Fas/FasL (显示 FASL 抗体)-apoptotic pathway is also involved in restricting tissue remodelling and dermal fibrosis during AD.
Hrd1 (显示 SYVN1 抗体)-null B cells exhibited high Fas expression during activation and rapidly underwent Fas-mediated apoptosis, which could be largely inhibited by FasL (显示 FASL 抗体) neutralization. Fas mutation in Hrd1 (显示 SYVN1 抗体) KO mice abrogated the increase in B-cell AICD. We identified Hrd1 (显示 SYVN1 抗体) as the first E3 ubiquitin ligase (显示 MUL1 抗体) of the death receptor Fas and Hrd1 (显示 SYVN1 抗体)-mediated Fas destruction as a molecular mechanism in regulating B-cell immunity.
FAS contributes to mitochondrial dysfunction, steatosis development, and insulin (显示 INS 抗体) resistance under high fat diet.
anti-apoptotic molecules BclxL (显示 BCL2L1 抗体) and Bcl-2 (显示 BCL2 抗体) and the pro-apoptotic factors BAD and BID (显示 BID 抗体) cooperate to promote migration of triple-negative breast cancer cells stimulated with cl-CD95L (显示 FASL 抗体).
These findings reveal a role for MOAP-1 (显示 MOAP1 抗体) in Fas signaling in the liver by promoting MTCH2 (显示 MTCH2 抗体)-mediated tBid recruitment to mitochondria.
The in vivo delivery of CRISPR/Cas9 could maintain liver homeostasis and protect hepatocytes from Fas-mediated cell apoptosis in the fulminant hepatic failure model.
Fas was expressed on fetal pig pancreatic cells, both beta and non-beta cells, and the level of expression could be upregulated by exposure to interleukin 1beta
The expression of FAS and FAS ligand (显示 FASL 抗体) in splenic macrophages co-infected with porcine circovirus 2 and porcine reproductive and respiratory syndrome virus is reported
The present results may provide some insights to understand the role of Fas/FasL (显示 FASL 抗体) in the spinal cord but not motor cortex with neuronal apoptosis and neuroplasticity in monkeys subjected to hemisection spinal cord injury.
Ligustrazine has notable protective effects on pulmonary ischemia/reperfusion injury inhibiting Fas/FasL (显示 FASL 抗体) mRNA express in lung tissue and decreasing apoptosis.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
APO-1 cell surface antigen
, CD95 antigen
, Delta Fas/APO-1/CD95
, FAS 827dupA
, FASLG receptor
, Fas (TNF receptor superfamily, member 6)
, Fas AMA
, TNF receptor superfamily member 6
, apoptosis antigen 1
, apoptosis-mediating surface antigen FAS
, tumor necrosis factor receptor superfamily member 6
, tumor necrosis factor receptor superfamily, member 6
, Fas antigen
, 14-3-3 protein zeta/delta
, factor activating exoenzyme S
, protein kinase C inhibitor protein 1
, Fas (TNF receptor superfamily member)
, apo-1 antigen
, Fas antigen (ATP1)
, Fas receptor
, Tumor necrosis factor receptor superfamily, member 6
, apoptosis (APO-1) antigen 1 ( FAS ), member 6
, Fas receptor CD95