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p300 抗体

(E1A Binding Protein P300 (EP300))
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008].

102 results :

EP300 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN6140193
 
EP300 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B1 unconjugated
Pubmed 1 reference
产品编号 ABIN560748
 
EP300 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042372
 
EP300 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7434752
 
EP300 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7440794
 
EP300 适用: 人 WB, IP, ICC, IF, ChIP, ChIP-seq 宿主: 小鼠 Monoclonal NM11 unconjugated
产品编号 ABIN6972466
 
EP300 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7440791
 
EP300 适用: 人 WB, IHC, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B1 unconjugated
产品编号 ABIN790522
 
EP300 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263956
 
EP300 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7D8A6 unconjugated
Pubmed 2 references
产品编号 ABIN969098
 
EP300 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7303740
 
EP300 适用: 人, 小鼠, 斑马鱼 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN800613
 
EP300 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN560747
 
EP300 适用: 人 WB 宿主: 兔 Polyclonal RB58228 unconjugated
产品编号 ABIN6242296
 
EP300 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7256534
 
EP300 适用: 人 DB 宿主: 兔 Polyclonal RB41431 unconjugated
Pubmed 5 references
产品编号 ABIN1881299
 
EP300 适用: 人 IHC (p), DB 宿主: 兔 Polyclonal RB7876 unconjugated
产品编号 ABIN389618
 
EP300 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1533367
 
EP300 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7295594
 
EP300 适用: 人, 小鼠, 大鼠, 猴, Mink WB, IP, ICC, IF 宿主: 小鼠 Monoclonal RW128 unconjugated
产品编号 ABIN363282
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Dot Blot (DB)
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunofluorescence (IF)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Chromatin Immunoprecipitation (ChIP)
    • ChIP DNA-Sequencing (ChIP-seq)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Enzyme Immunoassay (EIA)
    • Flow Cytometry (FACS)
    • Immunochromatography (IC)
    • Proximity Ligation Assay (PLA)
  • 适用
    • Human
    • Mouse
    • Rat
    • Zebrafish (Danio rerio)
    • Chicken
    • Cow
    • Dog
    • Mink
    • Monkey
    • Pig
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 1B1
    • 7D8A6
    • 9G412
    • AC240
    • NM11
    • RB08095
    • RB41431
    • RB58228
    • RB7876
    • RW128
  • 抗原表位
    • pSer1834
    • pSer89
    • N-Term
    • AA 2283-2414
    • AA 1351-1601
    • AA 731-830
    • AA 950-1000
    • C-Term
    • AA 1-158
    • AA 1000-1050
    • AA 55-104
    • AA 1-270
    • AA 1-50
    • AA 1451-1600
    • AA 1572-2371
    • AA 1807-1841
    • AA 2065-2414
    • AA 2124-2394
    • AA 2124-2397
    • AA 30-110
    • AA 51-150
    • AA 731-831
    • Glu83
    • Middle Region
    • Ser1834
    • Ser89
    • Val6
    • acLys1542
    • acLys1558
    • acLys1560
    • pThr2446
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
    • APC
    • PE
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
  • 抗体亚型
    • IgG
    • IgG1
    • Ig Fraction
    • IgG1 kappa
    • IgG3
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • ChIP-seq Grade
  • Supplier
    • antibodies-online
    • Signalway
    • Abbexa
    • Biomatik
    • Abcepta
    • Assay Biotechnology Company, Inc.
    • Cohesion Biosciences
    • Boster Bio
    • Acris
    • Covalab
    • Diagenode
    • Rockland
    • USBio

Latest Publications for our p300 抗体

Latorre-Muro, Baeza, Armstrong, Hurtado-Guerrero, Corzana, Wu, Sinclair, López-Buesa, Carrodeguas, Denu: "Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions." in: Molecular cell, Vol. 71, Issue 5, pp. 718-732.e9, (2019) (PubMed).

Dhar, Zhao, Lin, Gu, Pal, Wu, Alam, Lv, Yun, Gopalakrishnan, Flores, Northcott, Rajaram, Li, Shilatifard, Sillitoe, Chen, Lee: "MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes." in: Molecular cell, Vol. 70, Issue 5, pp. 825-841.e6, (2018) (PubMed).

Xiao, Ye, Zhou, Huang, Liu, Huang, Zhu, Wu, Zhang, Cai: "Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway." in: Archives of biochemistry and biophysics, Vol. 640, pp. 37-46, (2018) (PubMed).

Lee, Huang, Chang, Huang, Hsieh, Chen, Chou, Chiang, Lai, Shiau: "Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions." in: Scientific reports, Vol. 6, pp. 29311, (2016) (PubMed).

Luo, Chen, Chen, Alkam, Wang, Semenza: "PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia." in: Oncotarget, Vol. 7, Issue 6, pp. 6379-97, (2016) (PubMed).

Paladino, Yue, Furuya, Acoba, Rosser, Turkson: "A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer." in: Oncotarget, Vol. 7, Issue 6, pp. 7253-67, (2016) (PubMed).

Zhang, Zhang, Xiao, Liu, Wang, Gao, Rong, Yao, Li, Xu: "The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway." in: Biochemical pharmacology, Vol. 101, pp. 100-11, (2016) (PubMed).

Aubry, Shin, Crary, Lefort, Qureshi, Lefebvre, Califano, Shelanski: "Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120352, (2015) (PubMed).

Yi, Wang, Feng, Pintilie, Foulds, Lanz, Ludtke, Schmid, Chiu, OMalley: "Structure of a biologically active estrogen receptor-coactivator complex on DNA." in: Molecular cell, Vol. 57, Issue 6, pp. 1047-58, (2015) (PubMed).

He, Zheng, Zhang, Zhang, Wang, Yang, Sun, Wu, Wen: "KLF4 mediates the link between TGF-β1-induced gene transcription and H3 acetylation in vascular smooth muscle cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 9, pp. 4059-70, (2015) (PubMed).

Aliases for p300 抗体

E1A binding protein p300 (EP300) 抗体
histone acetyltransferase p300 (LOC446056) 抗体
E1A binding protein p300 (ep300) 抗体
E1A binding protein p300 (Ep300) 抗体
A430090G16 抗体
A730011L11 抗体
KAT3B 抗体
p300 抗体
p300 HAT 抗体
RSTS2 抗体
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