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p300 抗体 (AA 1572-2371)

EP300 适用: 人, 小鼠, 大鼠, 猴, Mink WB, IP, IF, ICC 宿主: 小鼠 Monoclonal RW128 unconjugated
产品编号 ABIN363282
发货至: 中国
  • 抗原 See all p300 (EP300) 抗体
    p300 (EP300) (E1A Binding Protein P300 (EP300))
    抗原表位
    • 35
    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1572-2371
    适用
    • 85
    • 41
    • 25
    • 15
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 猴, Mink
    宿主
    • 77
    • 12
    小鼠
    克隆类型
    • 78
    • 11
    单克隆
    标记
    • 50
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This p300 antibody is un-conjugated
    应用范围
    • 63
    • 42
    • 36
    • 20
    • 16
    • 15
    • 15
    • 13
    • 11
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Reacts with human p300 protein (residues 1868-1921)
    交叉反应
    小鼠
    交叉反应 (详细)
    Cross reacts with proteins from mouse, rat, monkey and mink.
    纯化方法
    Purified (protein A)
    免疫原
    Fusion protein containing residues 1572-2371 of human p300
    克隆位点
    RW128
    亚型
    IgG1 kappa
    Top Product
    Discover our top product EP300 Primary Antibody
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    ICC/IF1:10-1:2000, IP1:10-1:500, WB1:250-1:500

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.4, Sodium azide 0.1 %
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C/-80 °C
    储存方法
    Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
  • 抗原
    p300 (EP300) (E1A Binding Protein P300 (EP300))
    别名
    p300 (EP300 产品)
    别名
    KAT3B antibody, RSTS2 antibody, p300 antibody, A430090G16 antibody, A730011L11 antibody, p300 HAT antibody, E1A binding protein p300 antibody, histone acetyltransferase p300 antibody, EP300 antibody, LOC446056 antibody, ep300 antibody, Ep300 antibody
    背景
    Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. Mediates acetylation of histone H3 at 'Lys-122' (H3K122ac), a modification that localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability.
    基因ID
    2033
    UniProt
    Q09472
    途径
    p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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