p21 抗体
(Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| p21 抗体 (pSer125) (FITC) | 小鼠 | 兔 Polyclonal |
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| p21 抗体 (pSer125) (Biotin) | 小鼠 | 兔 Polyclonal |
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| p21 抗体 (pSer78) (Biotin) | 小鼠 | 兔 Polyclonal |
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| p21 抗体 (pThr145) (FITC) | 人 | 兔 Polyclonal |
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| p21 抗体 (pThr57) (FITC) | 人 | 兔 Polyclonal |
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| p21 抗体 (pSer125) (HRP) | 小鼠 | 兔 Polyclonal |
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| p21 抗体 (pSer78) (HRP) | 小鼠 | 兔 Polyclonal |
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| p21 抗体 (pThr57) (Biotin) | 人 | 兔 Polyclonal |
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| p21 抗体 (pSer130) (Biotin) | 人 | 兔 Polyclonal |
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| p21 抗体 (AA 105-140) (PE) | 人 | 兔 Polyclonal |
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| p21 抗体 (pSer130) (PE) | 人 | 兔 Polyclonal |
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| p21 抗体 (pThr145) (HRP) | 人 | 兔 Polyclonal |
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| p21 抗体 (AA 117-146) (HRP) | 人, 小鼠 | 兔 Polyclonal |
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| p21 抗体 (AA 134-164) (HRP) | 人 | 兔 Polyclonal |
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| p21 抗体 (AA 117-146) (FITC) | 人, 小鼠 | 兔 Polyclonal |
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| p21 抗体 (AA 134-164) (FITC) | 人 | 兔 Polyclonal |
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| p21 抗体 (AA 58-77) | 人 | 小鼠 Monoclonal |
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| p21 抗体 (AA 139-164) | 人 | 兔 Polyclonal |
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| Recombinant p21 抗体 (AA 120-138) | 人, 小鼠 | 兔 Chimeric |
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| Recombinant p21 抗体 (AA 120-138) | 人, 小鼠 | 大鼠 Monoclonal |
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Primary Antibody
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- pSer125
Primary Antibody
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- pSer125
Primary Antibody
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- pSer78
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- pThr145
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- pThr57
Primary Antibody
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- pSer125
Primary Antibody
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- pSer78
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- pThr57
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- pSer130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 105-140
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- pSer130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- pThr145
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 117-146
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 134-164
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 117-146
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 134-164
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 58-77
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 139-164
Primary Antibody
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Chimeric
- 克隆
- Y13-238
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, lambda
- 抗原表位
- AA 120-138
Primary Antibody
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 大鼠
- 克隆形成能力
- Monoclonal
- 克隆
- Y13-238
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG2a, lambda
- 抗原表位
- AA 120-138
Latest Publications for our p21 抗体
: "Evidence that SARS-CoV-2 Induces Lung-Cell Senescence: Potential Impact on COVID-19 Lung Disease." in: American journal of respiratory cell and molecular biology, (2021) (PubMed).
: "Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A." in: Molecular medicine reports, Vol. 22, Issue 5, pp. 3873-3885, (2021) (PubMed).
: "p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence." in: Matrix biology : journal of the International Society for Matrix Biology, (2019) (PubMed).
: "Luteolin modulates gene expression related to steroidogenesis, apoptosis, and stress response in rat LC540 tumor Leydig cells." in: Cell biology and toxicology, (2019) (PubMed).
: "Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells." in: Experimental cell research, Vol. 370, Issue 2, pp. 292-302, (2018) (PubMed).
: "LncRNA GACAT3 acts as a competing endogenous RNA of HMGA1 and alleviates cucurbitacin B-induced apoptosis of gastric cancer cells." in: Gene, (2018) (PubMed).
: "Dicer1 downregulation by multiple myeloma cells promotes the senescence and tumor-supporting capacity and decreases the differentiation potential of mesenchymal stem cells." in: Cell death & disease, Vol. 9, Issue 5, pp. 512, (2018) (PubMed).
: "Cullin3/KCTD5 induces monoubiquitination of ΔNp63α and impairs its activity." in: FEBS letters, Vol. 592, Issue 13, pp. 2334-2340, (2018) (PubMed).
: "Radiation-induced premature cellular senescence involved in glomerular diseases in rats." in: Scientific reports, Vol. 8, Issue 1, pp. 16812, (2018) (PubMed).
: "DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 7, pp. E1224-E1233, (2017) (PubMed).
: "Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A." in: Molecular medicine reports, Vol. 22, Issue 5, pp. 3873-3885, (2021) (PubMed).
: "p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence." in: Matrix biology : journal of the International Society for Matrix Biology, (2019) (PubMed).
: "Luteolin modulates gene expression related to steroidogenesis, apoptosis, and stress response in rat LC540 tumor Leydig cells." in: Cell biology and toxicology, (2019) (PubMed).
: "Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells." in: Experimental cell research, Vol. 370, Issue 2, pp. 292-302, (2018) (PubMed).
: "LncRNA GACAT3 acts as a competing endogenous RNA of HMGA1 and alleviates cucurbitacin B-induced apoptosis of gastric cancer cells." in: Gene, (2018) (PubMed).
: "Dicer1 downregulation by multiple myeloma cells promotes the senescence and tumor-supporting capacity and decreases the differentiation potential of mesenchymal stem cells." in: Cell death & disease, Vol. 9, Issue 5, pp. 512, (2018) (PubMed).
: "Cullin3/KCTD5 induces monoubiquitination of ΔNp63α and impairs its activity." in: FEBS letters, Vol. 592, Issue 13, pp. 2334-2340, (2018) (PubMed).
: "Radiation-induced premature cellular senescence involved in glomerular diseases in rats." in: Scientific reports, Vol. 8, Issue 1, pp. 16812, (2018) (PubMed).
: "DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 7, pp. E1224-E1233, (2017) (PubMed).
Aliases for p21 抗体
cyclin D1 (CCND1) 抗体cyclin dependent kinase inhibitor 1A (CDKN1A) 抗体
cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a) 抗体
cyclin-dependent kinase inhibitor 1A (Cdkn1a) 抗体
cyclin-dependent kinase inhibitor 1A L homeolog (cdkn1a.L) 抗体
cyclin-dependent kinase inhibitor 1 (cki1) 抗体
cyclin-dependent kinase inhibitor 1A (cdkn1a) 抗体
cyclin dependent kinase inhibitor 1A (Cdkn1a) 抗体
KRAS proto-oncogene, GTPase (KRAS) 抗体
CAP20 抗体
cap20 抗体
CCND1 抗体
CDKI 抗体
CDKN1 抗体
Cdkn1 抗体
cdkn1 抗体
CDKN1A 抗体
CIP1 抗体
Cip1 抗体
cip1 抗体
KRAS2 抗体
MDA-6 抗体
mda-6 抗体
mda6 抗体
p16Xic2 抗体
P21 抗体
p21 抗体
p21CIP1 抗体
p21Cip1 抗体
p21cip1 抗体
p21ras 抗体
p21WAF 抗体
SDI1 抗体
sdi1 抗体
si:ch1073-48m5.2 抗体
UV96 抗体
WAF1 抗体
Waf1 抗体
waf1 抗体
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