PAX8 抗体
(Paired Box 8 (PAX8))
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010].
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Latest Publications for our PAX8 抗体
: "PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors." in: eLife, Vol. 8, (2020) (PubMed).: "PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression." in: Oncology letters, Vol. 18, Issue 6, pp. 6732-6740, (2019) (PubMed).
: "GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation." in: The Journal of clinical investigation, (2018) (PubMed).
: "The PAX8 cistrome in epithelial ovarian cancer." in: Oncotarget, Vol. 8, Issue 65, pp. 108316-108332, (2018) (PubMed).
: "Renal cancer: new models and approach for personalizing therapy. ..." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 217, (2018) (PubMed).
: "BCOR-CCNB3 Undifferentiated Sarcoma-Does Immunohistochemistry Help in the Identification?" in: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, Vol. 20, Issue 4, pp. 321-329, (2017) (PubMed).
: "Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors." in: JCI insight, Vol. 1, Issue 13, (2016) (PubMed).
: "Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury." in: Scientific reports, Vol. 5, pp. 8826, (2015) (PubMed).
: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." in: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) (PubMed).
: "Fluorescence in situ hybridization analysis using PAX8- and PPARG-specific probes reveals the presence of PAX8-PPARG translocation and 3p25 aneusomy in follicular thyroid neoplasms." in: Cancer genetics and cytogenetics, Vol. 196, Issue 1, pp. 7-13, (2009) (PubMed).
Aliases for PAX8 抗体
paired box 8 (PAX8) 抗体paired box 8 (pax8) 抗体
paired box 8 (Pax8) 抗体
paired box 8 L homeolog (pax8.L) 抗体
pax-8 抗体
PAX-8 抗体
Pax-8 抗体
PAX8 抗体
XPax-8 抗体
XPax8 抗体
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