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Patched 1 抗体

(Patched 1 (PTCH1))
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008].

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  • 抗原: Patched 1 (PTCH1)
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7809343
Recombinant Patched 1 抗体 PTCH1 · Primary Antibody 人 Alpaca Monoclonal 克隆位点 SAA1343
  • 100 μg
发货至: 中国
ABIN6086716
Patched 1 抗体 (AA 1180-1411) (FITC) PTCH1 · Primary Antibody 人 兔 Polyclonal
  • ELISA (ELISA: 所列应用)
  • 100 μL
  • 20 μL
  • 50 μL
发货至: 中国
ABIN2344561
Patched 1 抗体 (AA 841-941) PTCH1 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 1G2
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN6891968
Patched 1 抗体 (Alexa Fluor 555) PTCH1 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6908031
Patched 1 抗体 (Alexa Fluor 680) PTCH1 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6850596
Patched 1 抗体 (Alexa Fluor 647) PTCH1 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6859842
Patched 1 抗体 (Alexa Fluor 750) PTCH1 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6835652
Patched 1 抗体 (Alexa Fluor 594) PTCH1 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6819589
Patched 1 抗体 (Alexa Fluor 488) PTCH1 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN1737879
Patched 1 抗体 (AA 269-279) PTCH1 · Primary Antibody 人, 小鼠, 大鼠, 小鸡 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN188468
Patched 1 抗体 (AA 269-279) PTCH1 · Primary Antibody 小鸡 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 0.1 mL
  • 100 μg
发货至: 中国
Primary Antibody
适用
人
宿主
Alpaca
克隆形成能力
Monoclonal
克隆
SAA1343
标记
unconjugated
Fragment
single-domain Antibody (sdAb)
蛋白类型
Recombinant Antibody
产品编号 ABIN7809343
Primary Antibody
  • ELISA (ELISA: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
FITC
抗体亚型
IgG
抗原表位
AA 1180-1411
产品编号 ABIN6086716
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
1G2
标记
unconjugated
抗体亚型
IgG2a kappa
抗原表位
AA 841-941
产品编号 ABIN2344561
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 555
产品编号 ABIN6891968
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 680
产品编号 ABIN6908031
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 647
产品编号 ABIN6850596
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 750
产品编号 ABIN6859842
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 594
产品编号 ABIN6835652
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 488
产品编号 ABIN6819589
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
适用
人, 小鼠, 大鼠, 小鸡
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 269-279
产品编号 ABIN1737879
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
小鸡
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗原表位
AA 269-279
产品编号 ABIN188468

Latest Publications for our Patched 1 抗体

Hasanovic, Ruggiero, Jung, Rapa, Signetti, Ben Hadj, Terzolo, Beuschlein, Volante, Hantel, Lalli, Mus-Veteau: "Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo." in: International journal of cancer, Vol. 143, Issue 1, pp. 199-211, (2019) (PubMed).

Takeuchi, Kito, Itoh, Naruse, Fujikawa, Sadek, Akiyama, Yamashiro, Wakisaka, Abe: "Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling." in: Experimental cell research, Vol. 371, Issue 2, pp. 417-425, (2018) (PubMed).

Wetendorf, Wu, Wang, Creighton, Wang, Lanz, Blok, Tsai, Tsai, Lydon, DeMayo: "Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment." in: Biology of reproduction, Vol. 96, Issue 2, pp. 313-326, (2017) (PubMed).

Zhang, Nan, Song, Wang, Si, Li: "Knockdown of HIF-1α inhibits the proliferation and migration of outer root sheath cells exposed to hypoxia in vitro: An involvement of Shh pathway." in: Life sciences, Vol. 191, pp. 82-89, (2017) (PubMed).

Wang, Song, Anbarchian, Shirazyan, Sadik, Lyons: "Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate." in: PLoS genetics, Vol. 12, Issue 10, pp. e1006352, (2016) (PubMed).

Meerang, Bérard, Felley-Bosco, Lauk, Vrugt, Boss, Kenkel, Broggini-Tenzer, Stahel, Arni, Weder, Opitz: "Antagonizing the Hedgehog Pathway with Vismodegib Impairs Malignant Pleural Mesothelioma Growth In Vivo by Affecting Stroma." in: Molecular cancer therapeutics, Vol. 15, Issue 5, pp. 1095-105, (2016) (PubMed).

Martinez, Kobayashi, Krishnan, Webber, Christie, Guo, Singh, Zochodne: "Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen." in: Experimental neurology, Vol. 271, pp. 493-505, (2015) (PubMed).

Xie, Zhang, Chen, Xie, Chen, Cheng, Zhou, Chen: "Developmental Status: Impact of Short-Term Ischemia on Follicular Survival of Whole Ovarian Transplantation in a Rabbit Model." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135049, (2015) (PubMed).

Abiria, Williams, Munden, Grover, Wallace, Lundberg, Valadez, Cooper: "Expression of Hedgehog ligand and signal transduction components in mutually distinct isocitrate dehydrogenase mutant glioma cells supports a role for paracrine signaling." in: Journal of neuro-oncology, Vol. 119, Issue 2, pp. 243-51, (2014) (PubMed).

Jeng, Sheen, Jeng, Yu, Hsiau, Chang: "High expression of Sonic Hedgehog signaling pathway genes indicates a risk of recurrence of breast carcinoma." in: OncoTargets and therapy, Vol. 7, pp. 79-86, (2014) (PubMed).

Aliases for Patched 1 抗体

patched 1 (PTCH1) 抗体
patched 1 (ptch1) 抗体
patched 1 (Ptch1) 抗体
patched 1 L homeolog (ptch1.L) 抗体
Protein patched homolog 1 (ptc-1) 抗体
A230106A15Rik 抗体
BCNS 抗体
HPE7 抗体
lep 抗体
mes 抗体
NBCCS 抗体
patched 抗体
patched1 抗体
PTC 抗体
Ptc 抗体
Ptc-1 抗体
PTC1 抗体
ptc1 抗体
Ptc1 抗体
ptc2 抗体
PTCH 抗体
Ptch 抗体
Ptch2 抗体
PTCH11 抗体
XPtc1 抗体
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