(Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Rouleau, McDonald, Gagné, Ouellet, Droit, Hunter, Dutertre, Prigent, Hendzel, Poirier: "PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery." in: Journal of cellular biochemistry, Vol. 100, Issue 2, pp. 385-401, (2007) (PubMed).
Augustin, Spenlehauer, Dumond, Ménissier-De Murcia, Piel, Schmit, Apiou, Vonesch, Kock, Bornens, De Murcia: "PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression." in: Journal of cell science, Vol. 116, Issue Pt 8, pp. 1551-62, (2003) (PubMed).
Urbánek, Paces, Králová, Dvorák, Paces: "Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9." in: Folia biologica, Vol. 48, Issue 5, pp. 182-91, (2002) (PubMed).
Aliases for PARP3 抗体
seed maturation protein PM38 (PARP3) 抗体 poly (ADP-ribose) polymerase family, member 3 (parp3) 抗体 poly(ADP-ribose) polymerase family member 3 (PARP3) 抗体 poly(ADP-ribose) polymerase family member 3 L homeolog (parp3.L) 抗体 poly(ADP-ribose) polymerase family member 3 (parp3) 抗体 poly (ADP-ribose) polymerase family, member 3 (Parp3) 抗体 A930002C11Rik 抗体 ADPRT-3 抗体 ADPRT3 抗体 Adprt3 抗体 ADPRTL2 抗体 Adprtl3 抗体 ADPRTL3 抗体 ARTD3 抗体 AW990611 抗体 fj17c06 抗体 IRT1 抗体 PADPRT-3 抗体 pADPRT-3 抗体 PARP-3 抗体 PARP3 抗体 parp3 抗体 PM38 抗体 wu:fj17c06 抗体 zgc:66157 抗体