PARP3 抗体 (C-Term)
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北京 101111
Quick Overview for PARP3 抗体 (C-Term) (ABIN2778113)
抗原
See all PARP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PARP3 Antibody - C-terminal region
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序列
- LGREHHINTD NPSLKSPPPG FDSVIARGHT EPDPTQDTEL ELDGQQVVVP
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预测反应
- Cow: 92%, Dog: 91%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 85%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against PARP3. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PARP3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108441
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression." in: Journal of cell science, Vol. 116, Issue Pt 8, pp. 1551-62, (2003) (PubMed).
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- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
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别名
- PARP3
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背景
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Background Information: The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Name: poly(ADP-ribose) polymerase family member 3
Alternative Symbols: IRT1, ARTD3, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3
Protein Name: poly [ADP-ribose] polymerase 3
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分子量
- 59kDa
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基因ID
- 10039
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NCBI登录号
- NP_005476
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UniProt
- Q9Y6F1
抗原
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