(Poly (ADP-Ribose) Polymerase Family, Member 10 (PARP10))
Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008].
Shahrour, Nicolae, Edvardson, Ashhab, Galvan, Constantin, Abu-Libdeh, Moldovan, Elpeleg: "PARP10 deficiency manifests by severe developmental delay and DNA repair defect." in: Neurogenetics, Vol. 17, Issue 4, pp. 227-232, (2016) (PubMed).
Nicolae, Aho, Vlahos, Choe, De, Karras, Moldovan: "The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13627-37, (2014) (PubMed).
Aliases for PARP10 抗体
poly(ADP-ribose) polymerase family member 10 (PARP10) 抗体 poly (ADP-ribose) polymerase family, member 10 (Parp10) 抗体 ARTD10 抗体 PARP10 抗体