Parkin 抗体
(Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
The precise function of this gene is unknown\; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008].
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128 results
PARK2
适用: 人
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our Parkin 抗体
: "PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation." in: Redox biology, Vol. 26, pp. 101254, (2019) (PubMed).: "Triggering of Parkin Mitochondrial Translocation in Mitophagy: Implications for Liver Diseases." in: Frontiers in pharmacology, Vol. 7, pp. 100, (2016) (PubMed).
: "Restoring Pharmacologic Preconditioning in the Aging Heart: Role of Mitophagy/Autophagy." in: The journals of gerontology. Series A, Biological sciences and medical sciences, (2016) (PubMed).
: "Ethanol-induced mitophagy in liver is associated with activation of the PINK1-Parkin pathway triggered by oxidative DNA damage." in: Histology and histopathology, Vol. 31, Issue 10, pp. 1143-59, (2016) (PubMed).
: "Parkin modulates expression of HIF-1α and HIF-3α during hypoxia in gliobastoma-derived cell lines in vitro." in: Cell and tissue research, Vol. 364, Issue 3, pp. 465-74, (2016) (PubMed).
: "ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts." in: Scientific reports, Vol. 6, pp. 24700, (2016) (PubMed).
: "Expression pattern of parkin isoforms in lung adenocarcinomas." in: Tumour biology, (2015) (PubMed).
: "Neuroprotective effects of extract of Acanthopanax senticosus harms on SH-SY5Y cells overexpressing wild-type or A53T mutant ?-synuclein." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 5, pp. 704-11, (2014) (PubMed).
: "Alternative splicing generates different parkin protein isoforms: evidences in human, rat, and mouse brain." in: BioMed research international, Vol. 2014, pp. 690796, (2014) (PubMed).
: "Increasing the Coding Potential of Genomes Through Alternative Splicing: The Case of PARK2 Gene." in: Current genomics, Vol. 15, Issue 3, pp. 203-16, (2014) (PubMed).
Aliases for Parkin 抗体
parkin (park) 抗体parkin RBR E3 ubiquitin protein ligase (PRKN) 抗体
parkin RBR E3 ubiquitin protein ligase (Prkn) 抗体
parkin RBR E3 ubiquitin protein ligase (prkn) 抗体
parkin (CpipJ_CPIJ014867) 抗体
Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) 抗体
AR-JP 抗体
CG10523 抗体
Dmel\\CG10523 抗体
Dpark 抗体
dpk 抗体
LPRS2 抗体
Park 抗体
PARK2 抗体
PDJ 抗体
pdr-1 抗体
PRKN 抗体
Prkn 抗体
SD01679 抗体
si:ch211-123f21.1 抗体
zgc:112390 抗体
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