Osteoactivin 蛋白
(Osteoactivin (GPNMB))
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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15 results :
GPNMB
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
GPNMB
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS
1 image
GPNMB
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 85 % by SDS - PAGE
SDS
1 image
GPNMB
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AA, AP
1 image
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
GPNMB
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 90 % by SDS-PAGE.
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 98 % as determined by reducing SDS-PAGE.
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our Osteoactivin 蛋白
: "Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases." in: Journal of cellular physiology, Vol. 233, Issue 1, pp. 409-421, (2017) (PubMed).: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." in: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
Aliases for Osteoactivin 蛋白
glycoprotein nmb (Gpnmb) 蛋白glycoprotein nmb (GPNMB) 蛋白
glycoprotein (transmembrane) nmb (Gpnmb) 蛋白
glycoprotein nmb L homeolog (gpnmb.L) 蛋白
DC-HIL 蛋白
Dchil 蛋白
HGFIN 蛋白
ipd 蛋白
NMB 蛋白
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