Osteoactivin 蛋白
(Osteoactivin (GPNMB))
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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19 results
GPNMB
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AA, AP
1 image
GPNMB
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS
1 image
GPNMB
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 85 %
SDS
1 image
GPNMB
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by SDS-PAGE
1 image
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
GPNMB
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 90 % by SDS-PAGE.
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
GPNMB
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 98 % as determined by reducing SDS-PAGE.
GPNMB
宿主: 人
宿主: Mammalian Cells
Recombinant
> 90 %
Inactive
GPNMB
宿主: 人
宿主: Mammalian Cells
Recombinant
> 90 %
Inactive
GPNMB
宿主: 小鼠
宿主: Mammalian Cells
Recombinant
> 90 %
Inactive
GPNMB
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our Osteoactivin 蛋白
: "Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases." in: Journal of cellular physiology, Vol. 233, Issue 1, pp. 409-421, (2017) (PubMed).: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." in: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
Aliases for Osteoactivin 蛋白
glycoprotein nmb (Gpnmb) 蛋白glycoprotein nmb (GPNMB) 蛋白
glycoprotein (transmembrane) nmb (Gpnmb) 蛋白
glycoprotein nmb L homeolog (gpnmb.L) 蛋白
DC-HIL 蛋白
Dchil 蛋白
HGFIN 蛋白
ipd 蛋白
NMB 蛋白
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