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抗Human Retinoic Acid Receptor alpha 抗体:
抗Mouse (Murine) Retinoic Acid Receptor alpha 抗体:
抗Rat (Rattus) Retinoic Acid Receptor alpha 抗体:
Human Monoclonal Retinoic Acid Receptor alpha Primary Antibody for EMSA, ICC - ABIN2668711
Reichrath, Mittmann, Kamradt, Müller: Expression of retinoid-X receptors (-alpha,-beta,-gamma) and retinoic acid receptors (-alpha,-beta,-gamma) in normal human skin: an immunohistological evaluation. in The Histochemical journal 1997
Show all 2 Pubmed References
Human Monoclonal Retinoic Acid Receptor alpha Primary Antibody for IHC (p), ELISA - ABIN519635
Voss, Collin, Dixon, Thomas: Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity. in Developmental cell 2009
Human Polyclonal Retinoic Acid Receptor alpha Primary Antibody for IHC (p), IHC - ABIN268790
Farias, Ong, Ghyselinck, Nakajo, Kuppumbatti, Mira y Lopez: Cellular retinol-binding protein I, a regulator of breast epithelial retinoic acid receptor activity, cell differentiation, and tumorigenicity. in Journal of the National Cancer Institute 2005
Human Monoclonal Retinoic Acid Receptor alpha Primary Antibody for IHC (fro), WB - ABIN152363
Choi, Park, Sockanathan: Activated retinoid receptors are required for the migration and fate maintenance of subsets of cortical neurons. in Development (Cambridge, England) 2014
Our findings unveil a novel essential oncogenic activity of PML (显示 PML 抗体)/RARA in Acute promyelocitic leukemia
Findings reveal a previously unrecognized role of c-Myc (显示 MYC 抗体) as a potential ceRNA for PML (显示 PML 抗体)/RARalpha in acute promyelocytic leukemia (显示 PML 抗体).
RARalpha regulates Arp2/3-mediated actin cytoskeletal dynamics through a non-genomic signaling pathway
It has been shown that the AP-1 (显示 FOSB 抗体) family member JunB (显示 JUNB 抗体) and retinoic acid receptor alpha (RARa) mediate catalase (显示 CAT 抗体) transcriptional activation and repression, respectively, by controlling chromatin remodeling through a histone deacetylases-dependent mechanism.
Work identifies the TP53 (显示 TP53 抗体) tumor suppressor as a novel target through which NPM1 (显示 NPM1 抗体)-RARA impacts leukemogenesis.
Dual small interfering RNA (siRNA) silencing of RARalpha and RARgamma reversed RA blockade of P4-induced CK5 (显示 KRT5 抗体). Using promoter deletion analysis, we identified a region 1.1 kb upstream of the CK5 (显示 KRT5 抗体) transcriptional start site that is necessary for P4 activation and contains a putative progesterone response element (PRE
High RARA expression is associated with acute myeloid leukemia (显示 BCL11A 抗体).
Data suggest that the binding of Z-10 to RXRalpha (显示 RXRA 抗体) inhibited the interaction of RXRalpha (显示 RXRA 抗体) with PML (显示 PML 抗体)-RARalpha, leading to Z-10's selective induction of PML (显示 PML 抗体)-RARalpha degradation.
PML (显示 PML 抗体)-RARa bcr1 (显示 BCR 抗体) fusion is not responsible for colorectal tumor development.
overexpression of NLS (显示 ALDH1A2 抗体)-RARalpha promoted the proliferation of APL (显示 FASL 抗体) cells and inhibited their differentiation via the PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体) signaling pathway.
RARalpha competes with other PFN2a-binding proteins bearing PRMs and involved in actin filaments elongation. Consequently, the actin filament network is altered and MEFs adhesion is decreased. This novel role opens novel avenues for the understanding of pathologies characterized by increased levels of cytoplasmic RARalpha.
These data suggest that impairment of cardiac RARalpha signaling may be a novel mechanism that is directly linked to pathological stimuli-induced diastolic dysfunction.
Retinoic acid receptor alpha agonist all trans retinoic acid can protect the liver from ischemia reperfusion injury by promoting autophagy, which is dependent on Foxo3 (显示 FOXO3 抗体)/p-Akt (显示 AKT1 抗体)/Foxo1 (显示 FOXO1 抗体) signaling.
both the PML (显示 PML 抗体)-RARA-driven competitive transplantation advantage and development of acute promyelocytic leukemia (显示 PML 抗体) (APL (显示 FASL 抗体)) required DNMT3A (显示 DNMT3A 抗体)
the reprogramming of epiblast stem cells into embryonic stem cell-like cells also requires low levels of retinoic acid (RA), which can modulate Wnt (显示 WNT2 抗体) signalling through physical interactions of RARs (显示 RARS 抗体) with beta-catenin (显示 CTNNB1 抗体).
our findings challenge the predominant model in the field and we propose that PML (显示 PML 抗体)/RARA initiates leukemia by subtly shifting cell fate decisions within the promyelocyte compartment.
DNA-binding-defective PML (显示 PML 抗体)/RARA mutants could not repress the transcription of retinoic acid regulated genes.
although X-RARA fusion proteins have been suggested to act by blocking retinoid-dependent transcriptional programs , we observed a surprising paucity of natural retinoids capable of transactivating Gal4 (显示 LGALS4 抗体)-RARA in primary mouse bone marrow cells
The results indicate a physiological role for RARgamma as a negative regulator of osteoclastogenesis in vivo and in vitro, and reveal distinct influences of RARalpha and RARgamma in bone structure regulation.
Data suggest that retinoic acid and GM-CSF (显示 CSF2 抗体)-induced retinal dehydrogenase 2 (RALDH2 (显示 ALDH1A2 抗体)) expression in dendritic cells requires cooperative binding of transcription factor Sp1 (显示 SP1 抗体) via the RA receptor/retinoid X receptor (显示 RXRB 抗体) complex to the Aldh1a2 (显示 ALDH1A1 抗体) promoter.
Increased expression of mammary TRbeta1 (显示 THRB 抗体) and DIO2 (显示 DIO2 抗体), and decreased RXRalpha (显示 RXRA 抗体), provide a mechanism to increase thyroid hormone (显示 PTH 抗体) activity within the mammary gland during lactation.
results show role for retinoic acid receptor (显示 RARB 抗体) as a regulator of spatial patterning of the pre-placodal ectoderm (PPE)through Tbx1 and RIPPLY3; demonstrate that Ripply3, acting downstream of RAR (显示 RAB40B 抗体) signaling, is key player in establishing boundaries in the PPE
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
retinoic acid receptor alpha
, retinoic acid receptor, alpha
, retinoic acid receptor alpha-like
, nuclear receptor subfamily 1 group B member 1
, nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form
, retinoic acid nuclear receptor alpha variant 1
, retinoic acid nuclear receptor alpha variant 2
, retinoic acid receptor, alpha polypeptide
, RAR alpha 1
, rar alpha
, xRAR alpha
, retinoic acid receptor alpha 1 isoform